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  • Book
  • © 2014

Regenerative Medicine for the Inner Ear

Editors:

  • Broadens readers’ understanding of a new concept for regenerative medicine in the inner ear

  • Covers both basic and clinical aspects of regenerative inner ear treatments including topics on cochlear implants, hair cells, SGN and stem cells

  • Summarizes the latest studies on neuroprotection and regenerative medicine by leading authorities

  • Includes supplementary material: sn.pub/extras

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-xi
  2. Targets of Regenerative Medicine for the Inner Ear

    1. Front Matter

      Pages 1-1
    2. Anatomy of the Inner Ear

      • Tatsunori Sakamoto, Harukazu Hiraumi
      Pages 3-13
    3. Hair Cell

      • Norio Yamamoto
      Pages 23-30
    4. Stereocilia

      • Tomoko Kita, Tatsuya Katsuno, Shin-ichiro Kitajiri
      Pages 31-38
    5. Cochlear Lateral Wall

      • Takayuki Okano
      Pages 39-52
    6. Spiral Ganglion Cell and Auditory Neuron

      • Tetsuji Sekiya, Harukazu Hiraumi
      Pages 53-59
    7. Otolith

      • Yosuke Tona, Akiko Taura
      Pages 67-74
    8. Tectorial Membrane

      • Yosuke Tona, Tatsunori Sakamoto
      Pages 75-80
  3. Development of the Inner Ear

    1. Front Matter

      Pages 81-81
    2. Development and Regeneration

      • Norio Yamamoto
      Pages 83-90
    3. Otic Induction

      • Hiroe Ohnishi, Tatsunori Sakamoto
      Pages 91-99
    4. Cochlear Development

      • Tomoko Tateya
      Pages 101-113
    5. Vestibular Development

      • Hiroko Torii, Akiko Taura
      Pages 115-125
  4. Cochlear Implants

    1. Front Matter

      Pages 127-127
    2. Cochlear Implant: Past, Present, and Future

      • Hiroshi Yamazaki
      Pages 129-137
    3. Recent Progress in Cochlear Implant

      • Harukazu Hiraumi
      Pages 139-147
    4. Regenerative Medicine in Cochlear Implantation

      • Norio Yamamoto
      Pages 149-156

About this book

The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments. The book depicts the mechanisms that underlie inner ear diseases, their experimental models, and proposals for new strategies to treat their symptoms. As well, the exciting future prospects for dealing with the very common problem of inner ear diseases are explained. These disorders occur among many people and include sensorineural hearing loss (SNHL), sudden deafness, senile deafness, noise-induced deafness, tinnitus, dizziness–vertigo, and Ménière’s disease. In Japan alone, there are more than 6 million deaf patients including those with middle-range deafness. There is currently no effective treatment, and regardless of the underlying cause, the damage has been considered irreversible. However, the results of recent research show that these patients actually can recover. The study of hair cells, spiral ganglion neurons, and stem cells for inner ear diseases such as SNHL, tinnitus, dizziness, and vertigo is at the forefront of regenerative medicine and may provide solutions to some of these problems. The information presented here makes this book a valuable professional reference work for all doctors and researchers in the field of otolaryngology who focus on regenerative treatments for inner ear diseases.

Reviews

From the book reviews:

“This is an excellent text concerning differentiation and development of cochlear cells including outer and inner hair cells (OHCs; IHCs). … This is an outstanding book for developmental biologists, audiologists, neurophysiologists, from the beginning to advanced levels. Illustrations and line drawings are in full color and complement the discussion nicely.” (Joseph J. Grenier, Amazon.com, March, 2015)

Editors and Affiliations

  • Department of Otolaryngology-Head and Neck Surgery, Kyoto University Graduate School of Medicine, Sakyo-ku, Japan

    Juichi Ito

About the editor

Ito Juichi MD, PhD, Professor and Chairman of Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University.

Bibliographic Information

  • Book Title: Regenerative Medicine for the Inner Ear

  • Editors: Juichi Ito

  • DOI: https://doi.org/10.1007/978-4-431-54862-1

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Japan 2014

  • Hardcover ISBN: 978-4-431-54861-4Published: 19 August 2014

  • Softcover ISBN: 978-4-431-56389-1Published: 22 September 2016

  • eBook ISBN: 978-4-431-54862-1Published: 05 August 2014

  • Edition Number: 1

  • Number of Pages: XI, 321

  • Number of Illustrations: 17 b/w illustrations, 48 illustrations in colour

  • Topics: Otorhinolaryngology, Regenerative Medicine/Tissue Engineering, Head and Neck Surgery, Gene Therapy, Neurosciences

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access