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“Dr. Hayreh critically summarizes a vast and complicated array of literature on an often controversial topic. The conclusions are pertinent to a broad audience in neurology and ophthalmology, though the volume as a whole will likely draw the most interest from scholars of neuro-ophthalmology and related fields. … For the more typical reader … this serves to make each chapter accessible and informative in isolation. … The strength of this volume lies in its extensive, critical discussion of the literature with consistent style and message.” (Heather E. Moss, Neuro-Ophthalmology, Vol. 36 (3), 2012)