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  • © 2014

Omics Approaches in Breast Cancer

Towards Next-Generation Diagnosis, Prognosis and Therapy

Editors:

  • Up-to-date and complete information on omics of breast cancer

  • Chapters focus on early diagnosis, prognosis and targeted therapy

  • Covers breast cancer miRNA, lipidomics, pharmacogenomics, epigenomics, proteomics, nutrigenomics and stem cell

  • Includes supplementary material: sn.pub/extras

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xxviii
  2. Omics Approaches in Breast Cancer

    1. Front Matter

      Pages 1-1
    2. Omics Technologies Applied in Breast Cancer Research

      • Mariana Panal Cusati, Maria Herrera de la Muela, Ignacio Zapardiel
      Pages 3-15
    3. Omics of Hereditary Breast Cancer

      • Catherine A. Moroski-Erkul, Burak Yilmaz, Esra Gunduz, Mehmet Gunduz
      Pages 17-40
    4. Oncogenes and Tumor Suppressor Genes as a Biomarker in Breast Cancer

      • Eyyup Uctepe, Muradiye Acar, Esra Gunduz, Mehmet Gunduz
      Pages 41-51
    5. Breast Cancer Genomics

      • Birendra Kumar
      Pages 53-103
    6. Epigenomics of Breast Cancer

      • Kursat Oguz Yaykasli, Ertugrul Kaya, Emine Yaykasli
      Pages 105-126
    7. Nutrigenomics in Breast Cancer

      • Shailendra Dwivedi, Shailja Shukla, Apul Goel, Praveen Sharma, Sanjay Khattri, Kamlesh Kumar Pant
      Pages 127-151
    8. Long Noncoding RNAs in Breast Cancer: Implications for Pathogenesis, Diagnosis, and Therapy

      • Jaroslav Juracek, Robert Iliev, Marek Svoboda, Ondrej Slaby
      Pages 153-170
    9. Breast Cancer MicroRNAs: Clinical Biomarkers for the Diagnosis and Treatment Strategies

      • Gowhar Shafi, Tarique N. Hasan, Naveed Ahmed Syed, Ananta Paine, Jesper Tegner, Anjana Munshi
      Pages 171-182
    10. Breast Cancer Proteomics

      • Ida Pucci-Minafra
      Pages 183-209
    11. Metabolomics in Breast Cancer

      • Maria C. Calomarde, Javier De Santiago, Ignacio Zapardiel
      Pages 211-224
    12. Lipidomics in Breast Cancer

      • Alvin Kamili, Jennifer A. Byrne
      Pages 225-244
    13. Breast Cancer Stem Cells and Cellomics

      • Esin Demir, Bilge Atar, Dipali Dhawan, Debmalya Barh, Mehmet Gunduz, Esra Gunduz
      Pages 245-263
    14. Omics of Male Breast Cancer

      • Zahide Nur Unal, Gülhan Kaya, Debmalya Barh, Esra Gunduz, Mehmet Gunduz
      Pages 265-276
    15. Omics of Chemoresistant and Metastatic Breast Cancer

      • Margarita Aguilera, Juan Antonio Marchal
      Pages 277-295
    16. Animal Models of Breast Cancer

      • E. A. El-Abd, A. S. Sultan, E. A. Shalaby, F. Matalkah
      Pages 297-314
    17. In Silico Disease Models of Breast Cancer

      • Anjana Munshi, Vandana Sharma
      Pages 315-331
    18. Systems Biology and Integrative Omics in Breast Cancer

      • Enrique Hernández-Lemus
      Pages 333-352
  3. Breast Cancer: Next-Generation Diagnosis, Prognosis, and Therapy

    1. Front Matter

      Pages 353-353

About this book

Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.

Reviews

From the book reviews:

“This will be valuable for those who are interested in learning about various ‘omics’ approaches, findings in breast cancers through bioinformatics studies, and technical considerations of breast cancer diagnosis and treatment. … this book is well structured and contains an abundance of published findings. The area of ‘omics’ is essential to breast cancer research, and this book nicely summarizes and presents up-to-date findings.” (Shiuan Chen, Doody’s Book Reviews, March, 2015)

Editors and Affiliations

  • Institute of Integrative Omics, West Bengal, India

    Debmalya Barh

About the editor

Dr Debmalya Barh is the founder of Institute of Integrative Omics and Applied Biotechnology (IIOAB) at Nonakuri, Tamluk, West Bengal, India. His core competencies include bioinformatics, genome, genomics and proteomics, cell signaling, integrative omics based marker and target discovery, cancer pharmacogenomics, personalized medicine, cardiovascular and infectious diseases. He has been a consultant for three top healthcare and diagnostic companies in USA. He is the reviewer/editorial board member of many journals like CMAJ, Molecular Medicine, Bioinformatics, BMC Genomics, BMC Systems Biology, Journal of Medical Informatics, Current Oncology, Gene Therapy, J. Cardiovascular Dis Res, J Integrated Omics, AIOAB. He has several scientific publications including genome sequences, journal articles, book chapters and reference books.

Bibliographic Information

  • Book Title: Omics Approaches in Breast Cancer

  • Book Subtitle: Towards Next-Generation Diagnosis, Prognosis and Therapy

  • Editors: Debmalya Barh

  • DOI: https://doi.org/10.1007/978-81-322-0843-3

  • Publisher: Springer New Delhi

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer India 2014

  • Hardcover ISBN: 978-81-322-0842-6Published: 22 October 2014

  • Softcover ISBN: 978-81-322-3472-2Published: 22 September 2016

  • eBook ISBN: 978-81-322-0843-3Published: 13 October 2014

  • Edition Number: 1

  • Number of Pages: XXVIII, 545

  • Number of Illustrations: 25 b/w illustrations, 35 illustrations in colour

  • Topics: Oncology, Gynecology, Human Genetics, Pathology, Cancer Research

Buy it now

Buying options

eBook USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access