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Renal Tumors of Childhood

Biology and Therapy

  • Book
  • © 2014

Overview

Editors:
  1. Kathy Pritchard-Jones

    1. Department of Developmental Biology and Cancer, Institute of Child Health, University College London, London, United Kingdom

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    You can also search for this editor in PubMed   Google Scholar

  2. Jeffrey S. Dome

    1. Children's National Medical Center Center for Cancer & Blood Disorders, Washington, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Integrates state of the art information on biological advances and clinical dilemmas in a format that will be easily understandable for practising clinicians and research scientists
  • Documents the recent explosion in knowledge of molecular changes in the various childhood renal tumours
  • Details the different treatment approaches and discusses the incorporation of biologically targeted agents into front-line therapy
  • Includes supplementary material: sn.pub/extras

Part of the book series: Pediatric Oncology (PEDIATRICO)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Epidemiology of Renal Tumours of Childhood

    • Charles A. Stiller, Andrew F. Olshan
    Pages 1-17

  3. Genetic Predisposition to Wilms Tumour

    • Richard H. Scott, Nazneen Rahman
    Pages 19-38

  4. Clinical Presentation

    • Elizabeth Mullen, Norbert Graf
    Pages 39-52

  5. Pathology of Renal Tumours of Childhood

    • Gordan M. Vujanic
    Pages 53-76

  6. Treatment of Wilms Tumor in the Children’s Oncology Group

    • Conrad Fernandez
    Pages 77-99

  7. Treatment of Wilms Tumour: The SIOP Approach

    • Rhoikos Furtwängler, Kathy Pritchard-Jones
    Pages 101-118

  8. Treatment of Relapsed Wilms Tumor

    • Filippo Spreafico, Marcio H. Malogolowkin
    Pages 119-131

  9. Imaging

    • Geetika Khanna, Øystein E. Olsen
    Pages 133-152

  10. Biological Prognostic Factors in Wilms Tumors

    • Kathy Pritchard-Jones, Mariana Maschietto, Paul Grundy
    Pages 153-166

  11. Molecular-Targeted Therapy for Pediatric Renal Tumors

    • James I. Geller, Peter Hohenstein
    Pages 167-186

  12. Surgical Consideration for Wilms’ Tumors and Other Neoplastic Renal Lesions

    • Peter F. Ehrlich, Jan Godzinski
    Pages 187-206

  13. Radiotherapy for Wilms’ Tumour and Other Childhood Renal Cancers

    • Mark N. Gaze, John A. Kalapurakal
    Pages 207-227

  14. Late Effects and QOL Chapter

    • Gill A. Levitt, Daniel M. Green
    Pages 229-247

  15. Non-Wilms Pediatric Renal Tumors

    • Jeffrey S. Dome, Saskia L. Gooskens, M. M. van den Heuvel-Eibrink
    Pages 249-269

  16. Wilms Tumour in Countries with Limited Resources

    • Monika Metzger, Judith A. Wilimas, Mhamed Harif, Trijn Israels
    Pages 271-281
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Keywords

About this book

This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. All of the authors are experts from Europe and North America and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.

Editors and Affiliations

  • Department of Developmental Biology and Cancer, Institute of Child Health, University College London, London, United Kingdom

    Kathy Pritchard-Jones

  • Children's National Medical Center Center for Cancer & Blood Disorders, Washington, USA

    Jeffrey S. Dome

Bibliographic Information

  • Book Title: Renal Tumors of Childhood

  • Book Subtitle: Biology and Therapy

  • Editors: Kathy Pritchard-Jones, Jeffrey S. Dome

  • Series Title: Pediatric Oncology

  • DOI: https://doi.org/10.1007/978-3-662-44003-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2014

  • Hardcover ISBN: 978-3-662-44002-5Published: 20 February 2015

  • Softcover ISBN: 978-3-662-51918-9Published: 06 October 2016

  • eBook ISBN: 978-3-662-44003-2Published: 04 February 2015

  • Series ISSN: 1613-5318

  • Series E-ISSN: 2191-0812

  • Edition Number: 1

  • Number of Pages: X, 281

  • Number of Illustrations: 25 b/w illustrations, 55 illustrations in colour

  • Topics: Oncology, Surgical Oncology, Pediatrics, Pathology

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