Cancers of the Skin

1. Front Matter

   Pages I-XIV

   PDF

2. Prevention

   1. Front Matter

      Pages 1-1

      PDF

   2. Public Education in Skin Cancer World-Wide

      • Günter Burg

      Pages 3-6

   3. UV Protection and Skin Cancer

      • Reinhard Dummer, Tanja Maier

      Pages 7-12

3. UV Protection by Clothes

   1. Front Matter

      Pages 13-13

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   2. Role of Clothes in Sun Protection

      • Thilo Gambichler, Peter Altmeyer, Klaus Hoffmann

      Pages 15-25

   3. Sun Protective Clothing: 5 Years of Experience in Australia

      • Colin R. Roy, Peter H. Gies, Alan McLennan

      Pages 26-34

   4. European Standards for Protective Apparel Against UV Radiation

      • Jan Laperre, Fred Foubert

      Pages 35-41

   5. American Standards for UV-Protective Textiles

      • Kathryn L. Hatch

      Pages 42-47

   6. Activities of CIE DIV-6 (Photobiology and Photochemistry) in UV Protection and Clothing

      • Jean-Pierre Césarini

      Pages 48-54

   7. Comparison of Methods: Determination of UV Protection of Clothing

      • Thilo Gambichler, Peter Altmeyer, Klaus Hoffmann

      Pages 55-61

   8. Improving UV Protection by Clothing — Recent Developments

      • Uli Osterwalder, Hauke Rohwer

      Pages 62-69

   9. Dress Up for Sun Protection/Creation of Public Awareness

      • Pierre Césarini

      Pages 70-72

4. Melanoma

   1. Front Matter

      Pages 73-73

      PDF

   2. Pathogenesis

      1. The Precursors of Malignant Melanoma

         • A. Neil Crowson, Cynthia M. Magro, Ignacio Sanchez-Carpintero, Martin C. Mihm Jr

         Pages 75-84

      2. Interferon-α Sensitivity in Melanoma Cells: Detection of Potential Response Marker Genes

         • Ulrich Certa, Monika Seiler, Elisabetta Padovan, Giulio C. Spagnoli

         Pages 85-91

      3. Molecular Cytogenetics as a Diagnostic Tool for Typing Melanocytic Tumors

         • Boris C. Bastian

         Pages 92-99

      4. Loss of Heterozygosity and Microsatellite Instability in Acquired Melanocytic Nevi: Towards a Molecular Definition of the Dysplastic Nevus

         • Albert Rübben, Inja Bogdan, Elke-Ingrid Grußiendorf-Conen, Günter Burg, Roland Böni

         Pages 100-110

   3. Epidemiology

      1. The Changing Incidence and Mortality of Melanoma in Australia

         • Robin Marks

         Pages 113-121

   4. Diagnostic

      1. Why Is Epiluminescence Microscopy Important

         • Klaus Wolff

         Pages 125-132

Skin cancer is the most frequent malignancy in humans and its incidence is still increasing. This situation calls for major efforts to manage the disease. Preventive measures must include reduced UV exposure and an enhanced common awareness of skin lesions. Advanced surgical techniques allow safe removal with excellent cosmetic results. In many cases alternative treatment modalities such as radiotherapy, cryosurgery and photodynamic therapy are applicable. The development of optimal sun screens and UV-protective clothes, new tools for early diagnosis of malignant lesions including videomicroscopy, improved evaluation of biopsy material and new treatment schemes will contribute to better patient care. New developments in therapy including pegylated interferons, cytokine-inducing molecules, monoclonal antibodies and vaccination approaches using peptides, dendritic cells, viruses or nDNA give hope for well-tolerated and efficient treatments.

• Carcinom
• Staging
• melanoma
• prevention
• skin cancer
• surgery
• therapy

• Department of Dermatology, University of Zurich, Zürich, Switzerland

  Reinhard Dummer, Frank O. Nestle, Günter Burg

Policies and ethics