Building on the considerable expertise of the dysproteinemia unit at Mayo Clinic, this book spans the gamut from multiple myeloma, the most frequent and most serious of the monoclonal gammopathies, to the rarest related disorders. Laboratory evaluation, associations with nonhematologic disorders, monoclonal gammopathies of undetermined significance, the more obscure plasma cell dyscrasias, amyloidosis, other immunoglobulin deposition disorders, Waldenström macroglobulinemia, and Fanconi anemia are among the topics covered. Naturally, particular attention is paid to multiple myeloma: history, pathogenesis, clinical and laboratory diagnosis, modern therapy, and prognosis. Subsets of multiple myeloma such as solitary plasmacytoma, extramedullary plasmacytoma, and plasma cell leukemia are reviewed. This volume is designed to serve as a long-lasting reference for clinicians and scientists involved in the management of multiple myeloma and associated disorders.