Local Therapies for Glioma

1. Front Matter

   Pages I-IX

   PDF

2. Intraoperative imaging — MRI

   • Z. Ram, M. Hadani

   Pages 1-4

3. Stereotactic volumetric resection of gliomas

   • P. C. Warnke

   Pages 5-8

4. Fluorescence-guided resections of malignant gliomas — an overview

   • W. Stummer, H. J. Reulen, A. Novotny, H. Steppe, J. C. Tonn

   Pages 9-12

5. Postoperative Imaging after Brain Tumor Resection

   • M. Warmuth-Metz

   Pages 13-20

6. Preliminary Experience in Glioma Surgery with Intraoperative High-Field MRI

   • C. Nimsky, O. Ganslandt, B. v. Keller, R. Fahlbusch

   Pages 21-29

7. Awake Craniotomy in Glioma Surgery

   • J. Jääskeläinen, T. Randell

   Pages 31-35

8. External beam and conformal radiotherapy in the management of gliomas

   • S.C. Short

   Pages 37-43

9. Interstitial stereotactic radiosurgery

   • P. C. Warnke, K. Kopitzki, C. B. Ostertag

   Pages 45-50

10. Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma

    • P. Menei, J. -P. Benoit

    Pages 51-55

11. Non-invasive transcranial High Intensity Focused Ultrasound (HIFUS) under MRI thermometry and guidance in the treatment of brain lesions

    • J. Jääskeläinen

    Pages 57-60

12. Intracavitary Chemotherapy for Glioblastoma: Present Status and Future Directions

    • M. Westphal, K. Lamszusand, D. Hilt

    Pages 61-67

13. Intralesional radioimmunotherapy in the treatment of malignant glioma: clinical and experimental findings

    • C. Goetz, W. Rachinger, G. Poepper, M. Decker, F.-J. Gildehaus, S. Stocker et al.

    Pages 69-75

14. Intracavitary Treatment of Malignant Gliomas: Radioimmunotherapy Targeting Fibronectin

    • M. Ravic

    Pages 77-82

15. Comparing monoclonal antibodies and small peptidic hormones for local targeting of malignant gliomas

    • A. Merlo, J. Mueller-Brandand, H. R. Maecke

    Pages 83-91

16. Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma

    • F. W. Weber, F. Floeth, A. Asher, R. Bucholz, M. Berge, M. Pradoss et al.

    Pages 93-103

17. Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies

    • S. Kunwar

    Pages 105-111

18. Oncolytic viruses for treatment of malignant brain tumours

    • N. G. Rainov, H. Ren

    Pages 113-123

19. Gene therapy of gliomas

    • W. Hamel, M. Westphal

    Pages 125-135

20. Cell therapy using encapsulated cells producing endostatin

    • R. Bjerkvig, T.-A. Read, P. Vajkoczy, P. Aebischer, W. Pralong, S. Platt et al.

    Pages 137-141

In addition to surgery and radiotherapy, local treatment modalities for the management of brain tumours are increasingly being developed and clinically tested. This book describes for the first time basic tumour biology as well as all current procedures in progress at the most recent level of knowledge, presented by leading experts in the respective fields. Image guided resection procedures, fluorescence guided surgery, developments in interstitial radiosurgery are addressed, just as intracavitary chemotherapy and all current concepts and studies of interstitial targeted therapy. Owing to its topicality this book will remain for long the standard for this comprehensively treated subject.

• Surgery
• brain
• brain tumour
• glioma
• neurosurgery
• radiosurgery
• radiotherapy
• surgical oncology

• Klinik und Poliklinik für Neurochirurgie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

  M. Westphal

• Neurochirurgische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, München, Germany

  J.-C. Tonn

• Department of Neurosurgery, Tel Aviv Medical Center, Tel Aviv, Israel

  Z. Ram

Policies and ethics