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Presents state-of-the-art knowledge gleaned from revolutionary clinical trials
Explores exciting advances in novel therapeutics
Covers medical, surgical, and radiation oncology perspectives
Discusses new imaging techniques for myeloma bone disease
Discusses the use of new bone markers for monitoring disease progression
Features unique material of interest to both clinicians and researchers
This state-of-the-art book presents the forefront in the science and clinical management of myeloma bone disease. Assembling the work of the world's premier thought leaders, this book begins with sections on clinical presentation, imaging, and biochemical markers and then goes on to discuss radiation, surgical, and medical therapies. Specific chapters are devoted to bisphosphonates and novel therapeutic agents, such as RANKL inhibitors, Wnt signaling inhibitors, and IMiDs. The mechanisms of osteoclast activation and osteoblast suppression in multiple myeloma are also explored.
Myeloma Bone Disease is a valuable resource for medical, surgical, and radiation oncologists and cancer researchers.
Content Level »Professional/practitioner
Keywords »Bisphosphonates - Bone Disease - Bortezomib - Denosumab - Kyphoplasty - Multiple Myeloma - Osteoblasts - Osteoclasts - Osteonecrosis of the jaw - Radiation Therapy - Vertebroplasty - imaging - surgery