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Medicine - Oncology & Hematology | Targeted Cancer Therapy

Targeted Cancer Therapy

Kurzrock, Razelle, Markman, Maurie (Eds.)

2008, XII, 452p. 32 illus., 16 illus. in color.

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  • Details the drugs that directly impact the molecular abnormality that characterizes a tumor
  • Examines personalized medicine based on an understanding of underlying biologic mechanisms
  • Covers new emerging technologies in target identification, drug discovery, molecular markers, and imaging, which are rapidly changing the face of cancer
  • Looks at how to design drug combinations that can overcome drug resistance

In the era of personalized medicine, cancer treatment has become a model for the use of targeted therapeutics. Leaving behind the "one size fits all" approach to cancer care, this book provides the practicing oncologist with an overview of the advances in treatment and an understanding of the implementation of new therapeutic agents. Targeted Cancer Therapy is divided into twenty chapters covering specific hematologic malignancies and solid tumors, targeted and functional imaging, and combination therapies. Each disease specific chapter includes up-to-date information on investigational and FDA approved therapies which will enhance the reader’s ability to prescribe effective drug regimens. This includes combinations of therapies and therapeutic modalities to overcome drug resistance.

In a rapidly changing field, this book will enable clinicians to improve their ability to practice personalized health planning, make early diagnoses, and select optimal drugs for each patient with predictable side effects and outcomes. Poised to change the landscape in oncology, Targeted Cancer Therapy is essential for practicing and academic physicians, fellows, and residents.

Content Level » Professional/practitioner

Keywords » Combination Therapy - Cytostatic Agents - Cytoxic Agents - Molecular Markers - Monoclonal Antibodies - Personalized Medicine - Targeted Therapy - carcinoma - imaging

Related subjects » Cancer Research - Internal Medicine - Oncology & Hematology

Table of contents 

Chapter 1 Perspectives: Bench to Bedside and Back Jennifer Wheler, MD and Razelle Kurzrock, MD, FACP Chapter 2 Targeted Therapy in Acute Myelogenous Leukemia Elihu Estey, MD Chapter 3 Targeted Therapy in Breast Cancer Barbara S. Craft, MD; Stacy Moulder, MD, MSCI Chapter 4 Targeted Therapy in Chronic Lymphocytic Leukemia Apostolia-Maria Tsimberidou, MD, PhD; Michael J. Keating, MD Chapter 5 Targeted Therapy in Chronic Myeloid Leukemia Elias Jabbour, MD; Jorge Cortes MD, Hagop Kantarjian, MD Chapter 6 Targeted Therapy in Colorectal Cancer Scott Kopetz, MD Chapter 7 Targeted Therapy in Non-small Cell Lung Cancer David J. Stewart, MD, FRCPC Chapter 8 Targeted Therapy in Lymphoma Amanda Wedgwood, MSN; Anas Younes, MD Chapter 9 Targeted Therapy in Melanoma Michael Davies, MD, PhD; Sunil Patel, MD; Kevin B. Kim, MD Chapter 10 Targeted Therapy in Multiple Myeloma Yuhong Zhou, MD; Raymond Alexanian, MD; Michael Wang, MD Chapter 11 Targeted Therapy in Myelodysplastic Syndrome Alfonso Quintás-Cardama, MD; Hagop Kantarjian, MD; Guillermo Garcia-Manero, MD; Jorge Cortes, MD Chapter 12 Targeted Therapy in Epithelial Ovarian Cancer Maurie Markman, MD Chapter 13 Targeted Drug Therapy in Pancreatic Cancer Don L. Gibbons, MD, PhD; Robert A. Wolff MD, Gauri Varadhachary, MD Chapter 14 Targeted Therapy in Prostate Cancer Amado J. Zurita MD; John F. Ward, MD; Jeri Kim, MD Chapter 15 Targeted Therapy in Renal Cell Carcinoma Eric Jonasch, MD; Nizar Tannir, MD Chapter 16 Targeted Therapy of Sarcoma Joseph Ludwig, MD; Jonathan C. Trent , MD, PhD Chapter 17 Targeted and Functional Imaging Vikas Kundra, MD, PhD; Dawid Schellingerhout, MD; Edward F. Jackson, PhD Chapter 18 Combining Targeted Therapies David Hong, MD; Lakshmi Chintala, MD Chapter 19: Drug Development in Cancer Medicine: Challenges for Targeted Approaches Luis H. Camacho, MD, MPH Chapter 20: Toward Personalized Therapy for Cancer Sarah J. Welsh, PhD, Garth Powis, DPHIL

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