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Medicine - Oncology & Hematology | Principles of Research Methodology - A Guide for Clinical Investigators

Principles of Research Methodology

A Guide for Clinical Investigators

Supino, Phyllis G., Borer, Jeffrey S. (Eds.)

2012, XVI, 276 p. 55 illus.

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  • Based on a highly regarded and popular lecture series on research methodology
  • Comprehensive guide written by experts in the field
  • Emphasizes the essentials and fundamentals of research methodologies

Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.

Content Level » Professional/practitioner

Related subjects » Cardiology & Angiology - Internal Medicine - Neurology - Oncology & Hematology

Table of contents 





Chapter 1

Overview of the Research Process

Chapter 2

Developing a Research Problem

Chapter 3

The Research Hypothesis: Role and Construction

Chapter 4

Design and Interpretation of Observational Studies: Cohort, Case-Control and Cross-Sectional Designs

Chapter 5

Fundamental Issues in Evaluating the Impact of Interventions: Sources and Control of Bias

Chapter 6

Protocol Development and Preparation for a Clinical Trial

Chapter 7

Data Collection and Management in Clinical Research

Chapter 8

Constructing and Evaluating Self Report Measures


Chapter 9

Selecting and Evaluating Secondary Data: The Role of Systematic Reviews and Meta-Analysis

Chapter 10

Sampling Methodology: Implications for Drawing Conclusions from Clinical Research Findings

Chapter 11

Introductory Statistics in Medical Research

Chapter 12

Ethical Issues in Clinical Research

Chapter 13

How to Prepare a Scientific Paper

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