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Hereditary Colorectal Cancer

  • Book
  • © 2010

Overview

Editors:
  1. Miguel A. Rodriguez-Bigas

    1. M.D. Anderson Cancer Center, Surgical Oncology, The University of Texas, Houston, USA

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  2. Raul Cutait

    1. Associate Professor of Surgery, Brazilian Registry of Inherited, Colorec, University of São Paulo Medical School, Sao Paulo, Brazil

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  3. Patrick M. Lynch

    1. M.D. Anderson Cancer Center, Gastroenterology, The University of Texas, Houston, USA

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  4. Ian Tomlinson

    1. Cancer Research UK London Research Insti, Molecular and Population Genetics Labora, London, United Kingdom

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  5. Hans F.A. Vasen

    1. Medical Center, Gastroenterology, Leiden University, Leiden, Netherlands

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  • Hereditary nonpolyposis colorectal cancer (HNPCC), also known as the Lynch syndrome, has not yet been covered in one comprehensive text The basic and clinical knowledge related to hereditary colorectal cancer is expanding and evolving rapidly A panel of worldwide experts address the issues surrounding hereditary colorectal cancer
  • Includes supplementary material: sn.pub/extras

Part of the book series: MD Anderson Solid Tumor Oncology Series (MDA, volume 5)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xvii
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  2. History

    1. Front Matter

      Pages 1-1
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    2. History: Familial Adenomatous Polyposis

      • Susan K. Clark, Kay F. Neale, Robin K. S. Phillips
      Pages 3-14

    3. Historical Aspects of Lynch Syndrome

      • Henry T. Lynch, Megan P. Hitchins, Trudy G. Shaw, Jane F. Lynch, Hemant Roy
      Pages 15-42

  3. Basic Sciences and Genetics

    1. Front Matter

      Pages 43-43
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    2. Molecular Genetics of Familial Adenomatous Polyposis

      • Luis G. Carvajal-Carmona, Andrew Silver, Ian P. Tomlinson
      Pages 45-66

    3. DNA Mismatch Repair

      • C. Richard Boland
      Pages 67-85

    4. Basic Sciences and Genetics: Hamartomatous Polyposis

      • James R. Howe, Daniel Calva
      Pages 87-109

    5. Hyperplastic Polyposis Syndrome: Colorectal Cancer Predisposition

      • Joanne Young
      Pages 111-131

    6. MUTYH-Associated Polyposis

      • Jeremy P. Cheadle
      Pages 133-146

    7. Polymorphic Variation and Risk of Colorectal Cancer

      • Richard A. Hubner, Richard S. Houlston
      Pages 147-171

  4. Pathology

    1. Front Matter

      Pages 173-173
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    2. The Pathologist and the Phenotype of Hereditary Colorectal Cancer

      • Jeremy R. Jass
      Pages 175-194

  5. Clinical Science: Familial Adenomatous Polyposis

    1. Front Matter

      Pages 195-195
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    2. Genotype Phenotype Correlation in Familial Adenomatous Polyposis

      • Miguel A. Rodriguez-Bigas
      Pages 197-202

    3. Surgery for Familial Adenomatous Polyposis

      • James Church
      Pages 203-217

    4. Duodenal Adenomas in Familial Adenomatous Polyposis

      • Andrew Latchford, Brian Saunders
      Pages 219-237

    5. FAP-Associated Desmoid Tumours

      • Gabriela Moeslein
      Pages 239-251

    6. Attenuated Familial Adenomatous Polyposis: Diagnosis, Management, and Future Prognosis

      • Thérèse M. F. Tuohy, Randall W. Burt
      Pages 253-267

  6. Clinical Science: Hereditary Nonpolyposis Colorectal Cancer

    1. Front Matter

      Pages 269-269
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Keywords

About this book

Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

Reviews

“This unique book is designed as a consultative source for individuals involved in the care of patients with colorectal cancer and patients at risk due to familial genetic testing. … Genetics counselors, medical geneticists, surgeons, and oncology specialists would find this book extremely useful. … The intimidating subject of hereditary colorectal cancer is well reviewed and presented in an easy-to-read manner. A job well done.” (Luis F. Escobar, Doody's Book Reviews, October, 2018)


“This comprehensive book details basic scientific knowledge, clinically relevant algorithms, and the historical framework of hereditary colorectal cancer. … It is written for colorectal specialists, which may include surgeons, gastroenterologists, oncologists, and geneticists. … The book would be an excellent definitive reference for any medical library. … There is no comparable book, and the information it provides would be very difficult to obtain from other sources in such a well- balanced and complete presentation.” (Neal Wilkinson, Doody’s Review Service, January, 2011)

Editors and Affiliations

  • M.D. Anderson Cancer Center, Surgical Oncology, The University of Texas, Houston, USA

    Miguel A. Rodriguez-Bigas

  • Associate Professor of Surgery, Brazilian Registry of Inherited, Colorec, University of São Paulo Medical School, Sao Paulo, Brazil

    Raul Cutait

  • M.D. Anderson Cancer Center, Gastroenterology, The University of Texas, Houston, USA

    Patrick M. Lynch

  • Cancer Research UK London Research Insti, Molecular and Population Genetics Labora, London, United Kingdom

    Ian Tomlinson

  • Medical Center, Gastroenterology, Leiden University, Leiden, Netherlands

    Hans F.A. Vasen

Bibliographic Information

  • Book Title: Hereditary Colorectal Cancer

  • Editors: Miguel A. Rodriguez-Bigas, Raul Cutait, Patrick M. Lynch, Ian Tomlinson, Hans F.A. Vasen

  • Series Title: MD Anderson Solid Tumor Oncology Series

  • DOI: https://doi.org/10.1007/978-1-4419-6603-2

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2010

  • Hardcover ISBN: 978-1-4419-6602-5Published: 13 September 2010

  • Softcover ISBN: 978-1-4614-2662-2Published: 07 November 2012

  • eBook ISBN: 978-1-4419-6603-2Published: 10 September 2010

  • Edition Number: 1

  • Number of Pages: XVIII, 630

  • Topics: Oncology, Surgical Oncology, Gastroenterology

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