Management of Lung Cancer in Older People

1. Front Matter

   Pages i-xiii

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2. Background and Epidemiology

   1. Front Matter

      Pages 1-1

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   2. Basic Science of Lung Cancer in Older Patients

      • Morena Fasano, Flavia Cantile, Floriana Morgillo, Fortunato Ciardiello

      Pages 3-12

   3. Clinical Epidemiology and the Impact of Comorbidity on Treatment and Outcome

      • Maryska L. G. Janssen-Heijnen

      Pages 13-30

3. Special Considerations in the Management of Older Patients

   1. Front Matter

      Pages 31-31

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   2. Physiological Assessment and Cardiopulmonary Exercise Testing

      • Paul P. Walker, Malcolm West, Michael P. W. Grocott, Sandy Jack

      Pages 33-52

   3. A Practical Mini-Guide to Geriatric Assessment

      • Siri Rostoft Kristjansson

      Pages 53-63

   4. Impact of the Physiological Effects of Aging on the Pharmacokinetics and Pharmacodynamics of Systemic Lung Cancer Treatment

      • Antonio Rossi, Dario Cova, Silvana Leo, Lazzaro Repetto

      Pages 65-87

   5. Drug Interactions and Polypharmacy

      • Silvana Leo, Dario Cova, Antonio Rossi, Lazzaro Repetto

      Pages 89-106

4. Diagnostics

   1. Front Matter

      Pages 107-107

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   2. Selection of Appropriate Surgery for Early Lung Cancer

      • Michael T. Jaklitsch, Weston Sacco

      Pages 109-118

5. Non Small-Cell Lung Cancer: Treatment of Early Stages

   1. Front Matter

      Pages 119-119

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   2. Surgery: Indications and Issues

      • Lorenzo Spaggiari, Domenico Galetta

      Pages 121-132

   3. Is There a Role for Postoperative Radiotherapy in Elderly Patients with Early-Stage Non-small Cell Lung Cancer?

      • Nicolas Girard, Françoise Mornex

      Pages 133-140

   4. Is There a Role for Neoadjuvant Chemotherapy in Older Patients?

      • Alejandro Navarro, Enriqueta Felip

      Pages 141-150

   5. Curative Radiotherapy in Patients Inoperable for Medical Reasons

      • Naomi E. Verstegen, Suresh Senan

      Pages 151-162

6. Non Small-Cell Lung Cancer: Treatment of Locally Advanced Disease

   1. Front Matter

      Pages 163-163

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   2. Adjuvant Chemotherapy: Feasibility in the Elderly and Patient Selection

      • Alejandro Navarro, Enriqueta Felip

      Pages 165-172

   3. Locally Advanced Non-Small Cell Lung Cancer in the Elderly: What Combination of Therapy Is Best?

      • Steven E. Schild

      Pages 173-183

7. Non Small-Cell Lung Cancer: Treatment of Advanced Disease

   1. Front Matter

      Pages 185-185

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This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older lung cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.

• Geriatric
• Gerontology
• Lung Cancer
• surgical oncology

From the reviews:

“The editors have successfully compiled a timely review of the management of lung cancer, focusing on the issues that pertain specifically to older patients. … This anthology is designed for oncologists … as well as pulmonologists whose practice includes older patients with lung cancer. … This is an excellent resource for any clinician who cares for elderly patients with lung cancer, although the information is appropriate for clinicians caring for cancer patients of all sorts. The authors’ well-written contributions are up to date and instructive.” (Melissa L. Johnson, Doody’s Book Reviews, August, 2013)

• , Department of Oncology/Hematology, S.G. Moscati Hospital, Avellino, Italy

  Cesare Gridelli

• St Helens Teaching Hospital, University of Liverpool, St Helens, United Kingdom

  Riccardo A Audisio

Policies and ethics