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Table of contents (10 chapters)
Keywords
About this book
A number of `cancer families', in which several closely related individuals have suffered from various specific forms of cancer, have been studied by genetic epidemiologists. However, for the majority of cancer cases, little or no discernible genetic influence or family history is found. Recent research has discovered that for many of these `sporadic' (non-familial) cancer cases, defects or aberrations in certain metabolic genes not previously associated with genetic cancer risk may contribute to either causing the disease or at least increasing the chances of developing cancer. It is therefore possible that much of what has previously passed for `bad luck' may turn out to be a new type of `bad genes'.
Genetic Susceptibility to Cancer explains that this new idea of `bad genes' may contain an unexpected positive side. The carcinogenic effects of these metabolic genes, unlike those of the oncogenes and tumor suppressor genes that are responsible for the inherited cancer syndromes, can potentially be overcome or nullified.
Genetic Susceptibility to Cancer will provide a valuable reference for health professionals, researchers, clinicians and biomedical scientists who are interested in the current thinking in this critically important areaof cancer management.
Authors and Affiliations
Bibliographic Information
Book Title: Genetic Susceptibility to Cancer
Authors: Seymour Garte
Series Title: Developments in Oncology
DOI: https://doi.org/10.1007/978-1-4615-4989-5
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1998
Hardcover ISBN: 978-0-7923-8383-3Published: 30 November 1998
Softcover ISBN: 978-1-4613-7265-3Published: 02 November 2012
eBook ISBN: 978-1-4615-4989-5Published: 09 March 2013
Edition Number: 1
Number of Pages: XI, 137
Topics: Oncology, Veterinary Medicine/Veterinary Science, Human Genetics, Epidemiology, Public Health