Atlas of Lymphoscintigraphy and Sentinel Node Mapping

1. Front Matter

   Pages i-xxiii

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2. The Anatomy and Physiology of Lymphatic Circulation

   • Pieter J. Tanis, Omgo E. Nieweg

   Pages 1-5

3. The Pathophysiology of Lymphatic Circulation in Different Disease Conditions

   • Rossella Di Stefano, Paola Anna Erba, Giovanni D’Errico

   Pages 7-15

4. Methodological Aspects of Lymphoscintigraphy: Radiopharmaceuticals and Instrumentation

   • Paola Anna Erba, Giuseppina Bisogni, Alberto Del Guerra, Giuliano Mariani

   Pages 17-25

5. Methodological Aspects of Lymphoscintigraphy: Bicompartmental Versus Monocompartmental Radiocolloid Administration

   • Paola Anna Erba, Martina Sollini, Giovanni D’Errico, Giuliano Mariani

   Pages 27-38

6. Lymphoscintigraphy for the Differential Diagnosis of Peripheral Edema and Intracavitary Lymph Effusion

   • Paola Anna Erba, Martina Sollini, Roberto Boni

   Pages 39-86

7. The Sentinel Lymph Node Concept in Oncologic Surgery

   • Omgo E. Nieweg

   Pages 87-93

8. General Concepts on Radioguided Sentinel Lymph Node Biopsy: Preoperative Imaging, Intraoperative Gamma-Probe Guidance, Intraoperative Imaging, and Multimodality Imaging

   • Federica Orsini, Federica Guidoccio, Sergi Vidal-Sicart, Renato A. Valdés Olmos, Giuliano Mariani

   Pages 95-110

9. SPECT/CT Image Generation and Criteria for Sentinel Node Mapping

   • Renato A. Valdés Olmos, Sergi Vidal-Sicart

   Pages 111-119

10. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Breast Cancer

    • Gianpiero Manca, Manuel Tredici, Valerio Duce, Sara Mazzarri, Federica Orsini, Serena Chiacchio et al.

    Pages 121-167

11. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Cutaneous Melanoma

    • Sergi Vidal-Sicart, Renato A. Valdés Olmos

    Pages 169-198

12. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Head and Neck Cancers

    • Renato A. Valdés Olmos, W. Martin C. Klop, Oscar R. Brouwer

    Pages 199-223

13. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Non-Small-Cell Lung Cancer

    • Giuseppe Boni, Franca M. A. Melfi, Gianpiero Manca, Federico Davini, Giuliano Mariani

    Pages 225-229

14. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Cancers of the Gastrointestinal Tract

    • Carmen Balagué, José Luis Pallarés

    Pages 231-248

15. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Cancers of the Female Reproductive System

    • Pilar Paredes, Sergi Vidal-Sicart

    Pages 249-268

16. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Cancers of the Male Reproductive System

    • Oscar R. Brouwer, Willem Meinhardt, Simon Horenblas, Renato A. Valdés Olmos

    Pages 269-283

17. Preoperative and Intraoperative Lymphatic Mapping for Radioguided Sentinel Node Biopsy in Kidney and Bladder Cancers

    • Axel Bex, Oscar R. Brouwer, Renato A. Valdés Olmos

    Pages 285-293

Although lymphoscintigraphy was originally introduced into clinical routine for identification of the cause of peripheral edema, more recently it has been widely applied for radioguided biopsy of the sentinel lymph node in patients with solid cancers. The procedure is now considered crucial for adequate planning of oncologic surgery in a growing number of cancers. This atlas presents a collection of richly illustrated teaching cases that demonstrate the clinical relevance and impact of lymphoscintigraphy in different pathologic conditions. After introductory chapters on the anatomy, physiology, and pathophysiology of lymphatic circulation, the role of lymphoscintigraphy in differential diagnosis of peripheral edema and characterization of intracavitary lymph effusions is addressed. The principal focus of the book, however, is on the use of lymphoscintigraphic mapping for radioguided sentinel node biopsy in cutaneous melanoma and cancers at a range of anatomic sites. The most commonly observed lymphoscintigraphic patterns are depicted, and anatomic variants and technical pitfalls of the procedure receive careful attention. The role of tomographic multimodality imaging is also considered. The atlas will be an excellent learning tool for residents in nuclear medicine and other specialists with an interest in the field.

• Lymphedema
• Lymphoscintigraphy
• Radioguided Surgery
• Sentinel lymph node biopsy
• Teaching cases
• head and neck surgery
• surgical oncology

From the reviews:

“This new textbook written by leading European protagonists from Spain, Italy and the Netherlands provides a comprehensive and beautifully illustrated review of established and emerging aspects of radionuclide imaging of the lymphatic system. … highly commendable and is recommended as a valuable reference aid for all departments undertaking lymphatic imaging. It is also likely to be of interest to nuclear medicine, radiology and surgical trainees and to other specialists such as radiographers and clinical scientists involved in the provision of nuclear medicine services.” (Andrew Scarsbrook, RAD Magazine, September, 2013)

“The purpose is to provide an ideal learning tool for trainees in nuclear medicine and surgical oncology and for practitioners entering both fields. These worthy objectives are admirably met by this book. … It also should serve as a valuable reference for medical oncologists, radiation oncologists, and scientists. … This is an excellent quality book. … This book occupies a unique niche. … highly useful and timely addition to the field.” (Bennett S. Greenspan, Doody’s Book Reviews, July, 2013)

“This atlas presents a collection of richly illustrated teaching cases that demonstrate the clinical relevance and impact of lymphoscintigraphy … . No other book published to date has addressed the issues of lymphoscintigraphy with the same approach as that of this book … . an ideal learning tool, especially for residents in nuclear medicine and for specialists in nuclear medicine who are entering the field, as well as a useful integration aid for residents in surgery (especially oncological surgery) and for surgeons entering the field.” (Antonia Ferraro and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 40, 2013)

“This Atlas aims to disseminate knowledge about Nuclear Medicine lymphoscintigraphy procedures in the evaluation of the lymphatic system and detection in disease, most of allin cancer. … This book will be greatly appreciated by nuclear medicine physicians, oncologic surgeons, radiologists and trainees in this difficult field.” (Giampiero Beluffi, La radiologia medica, Vol. 118, 2013)

• Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy

  Giuliano Mariani, Gianpiero Manca, Federica Orsini

• Nuclear Medicine, Hospital Clínic Barcelona, Barcelona, Spain

  Sergi Vidal-Sicart

• Nuclear Medicine, Division of Diagnostic Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands

  Renato A. Valdés Olmos

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