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  • © 2003

Molecular Nuclear Medicine

The Challenge of Genomics and Proteomics to Clinical Practice

  • First book summarizing topics of molecular imaging
  • Leading international authorship
  • Includes supplementary material: sn.pub/extras

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Table of contents (33 chapters)

  1. Front Matter

    Pages I-XX
  2. Primary Topics

    1. Front Matter

      Pages 1-1
    2. Measurements of Biochemical Reactions In Vivo

      • Ludwig E. Feinendegen, Walton W. Shreeve, Henry N. Wagner Jr.
      Pages 3-29
    3. The Human Genome and Disease

      • Eberhard Passarge
      Pages 31-37
    4. Functional Genomics and Proteomics: Basics, Opportunities and Challenges

      • Nikolai Kley, Stefan Schmidt, Vivian Berlin, Hannes Loferer, Jeno Gyuris
      Pages 39-66
    5. Instrumentation for Measuring Metabolism

      • Peter F. Sharp, Andy Welch, Stephen McCallum
      Pages 99-120
    6. Modelling Metabolite and Tracer Kinetics

      • Albert H. Gjedde
      Pages 121-169
    7. Compound Delivery and Local Blood Flows

      • James B. Bassingthwaighte
      Pages 171-198
  3. Whole Body Processes

    1. Front Matter

      Pages 199-199
    2. Endothelium and Compound Transfer

      • Christopher A. Dawson, Said H. Audi, Gary S. Krenz, David L. Roerig
      Pages 201-216
    3. Coagulation and Peripheral Vascular Disease

      • Leonard Rosenthall
      Pages 217-231
    4. Molecular Imaging of Infection and Inflammation

      • Huub J. J. M. Rennen, Otto C. Boerman, Wim J. G. Oyen, Frans H. M. Corstens
      Pages 233-251
    5. Element Metabolism and Body Composition

      • Walton W. Shreeve, Richard N. Pierson Jr.
      Pages 253-300
    6. The Biology of Aging and Related Nuclear Medicine Studies

      • Richard N. Pierson Jr., Walton W. Shreeve
      Pages 301-325
  4. Organ Systems

    1. Front Matter

      Pages 355-355
    2. Endocrinology

      • Junji Konishi, Ben A. Dwamena, Milton D. Gross, Brahm Shapiro, Takashi Misaki, Masao Fukunaga et al.
      Pages 357-409

About this book

Nuclear Medicine techniques have advanced to such a degree that biochemical transparency of the human body has reached the doorstep of medical application. The book gives background, techniques and examples in an interdisciplinary approach to quantify biochemical reactions in vivo by regional imaging and in vitro analyses. The goal is to assess in vivo biochemical homeostatic circuits under control by genes and protein interactions. It becomes apparent how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships operating in vivo and thus can help eventually to bring functional genomics and proteomics to clinical medicine.

 

Reviews

From the reviews:

"The editors...have brilliantly analyzed [the revolution in Nuclear Medicine] by gathering an impressive set of data on genomics and proteomics... The book's emphasis on the potential applications of nuclear medicine hints at the complete transformaiton that will face this specialty in the near future...this [book] should be carefully read by all specialists and researchers in nuclear medicine and by clinicians in other fields who may find in it new fields of research or applications of their own discoveries or a way to solve clinical problems. What is more, decision makers will benefit from learning about the potential of this specialty and its future role in clinical medicine and biology." -- NEJM, April 2004

"With few exceptions, everything in nuclear medicine is molecular medicine. … In other words: what is new? The answer is this book, which focusses especially on molecular nuclear imaging and draws attention to our ability, knowledge and expertise … . This beautifully produced hard-bound volume contains carefully assembled data and in-depth discussion of the major fields of nuclear medicine. … Suffice to say that this book will remain on my desk for a long time to come." (E.K.J. Pauwels, European  Journal of Nuclear Medicine and Molecular Imaging, Vol. 31(5), 2004)

Editors and Affiliations

  • Heinrich-Heine-University Düsseldorf, Lindau, Germany

    Ludwig E. Feinendegen

  • Radiology and Medicine SUNY, Stonybrook, USA

    Walton W. Shreeve

  • Medical Department Brookhaven National Laboratory, Upton, USA

    Walton W. Shreeve

  • National Institutes of Health/Clinical Center, Bethesda, USA

    William C. Eckelman

  • Department of Nuclear Medicine, Sung-Ae General Hospital, Seoul, Korea

    Yong-Whee Bahk

  • Nuclear Medicine and Radiation Health Sciences, The Johns Hopkins University School of Hygiene and Public Health, Baltimore, USA

    Henry N. Wagner

About the editors

 Over six hundred fifty scientific publications, especially on cell biology, molecular nuclear medicine for in vivo analysis of biochemical reactions, cell responses to low doses of ionizing radiation and to strong static magnetic fields in single- and multi- cellular systems. - Member of numerous national and international advisory groups, committees, boards. Member, Northrhine-Westfalian Academy of Sciences, Germany. Vice-president, Committee for the Annual Meetings of Nobel Prize Winners in Lindau, Germany. Numerous scientific awards and prices. 

Bibliographic Information

  • Book Title: Molecular Nuclear Medicine

  • Book Subtitle: The Challenge of Genomics and Proteomics to Clinical Practice

  • Editors: Ludwig E. Feinendegen, Walton W. Shreeve, William C. Eckelman, Yong-Whee Bahk, Henry N. Wagner

  • DOI: https://doi.org/10.1007/978-3-642-55539-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2003

  • Hardcover ISBN: 978-3-540-00132-4Due: 25 June 2003

  • Softcover ISBN: 978-3-642-62427-8Published: 24 October 2012

  • eBook ISBN: 978-3-642-55539-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XX, 795

  • Topics: Nuclear Medicine, Imaging / Radiology, Cancer Research, Molecular Medicine, Hematology, Oncology

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access