PET and SPECT in Neurology

1. Front Matter

   Pages i-xxvi

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2. Basics

   1. Front Matter

      Pages 1-1

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   2. Nuclear Medicine Imaging Tracers for Neurology

      • Philip H. Elsinga

      Pages 3-30

   3. 18F-Fluorodeoxyglucose PET Procedures: Health Economic Aspects in Neurology

      • Renaud Guignard, Matthieu J. Ouvrier, Bruno Krug, Andreas Otte, Jacques Darcourt, Rudi A. J. O. Dierckx

      Pages 31-57

   4. Tracer Kinetic Modelling

      • Adriaan A. Lammertsma

      Pages 59-73

   5. Quantification in Brain SPECT: Noninvasive Cerebral Blood Flow Measurements Using 99mTc-Labeled Tracers

      • Hiroshi Matsuda

      Pages 75-91

   6. MRI/PET Brain Imaging

      • Michel Koole, Kathleen Vunckx, Jeroen Verhaeghe, Koen Van Laere, Peter Jan Van Laar

      Pages 93-137

   7. An Investigation of Statistical Power of [15O]-H2O PET Perfusion Imaging: The Influence of Delay and Time Interval

      • Rudie Kortekaas, Janniko R. Georgiadis

      Pages 139-148

   8. Molecular Imaging Using Magnetic Resonance Spectroscopy in Neurology: The Past, the Present, and the Future

      • Paul E. Sijens

      Pages 149-167

   9. The Default Network of the Brain

      • Koene R. A. Van Dijk, Alexander Drzezga

      Pages 169-181

3. Dementia

   1. Front Matter

      Pages 183-183

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   2. Dementia Due to Neurodegenerative Disease: Molecular Imaging Findings

      • Rik Ossenkoppele, Jan Booij, Philip Scheltens, Bart N. M. van Berckel

      Pages 185-211

   3. Aβ Imaging in Aging, Alzheimer’s Disease and Other Neurodegenerative Conditions

      • Victor L. Villemagne, Michelle Fodero-Tavoletti, Paul Yates, Colin L. Masters, Christopher C. Rowe

      Pages 213-254

   4. PET Imaging of the α4β2* Nicotinic Acetylcholine Receptors in Alzheimer’s Disease

      • Osama Sabri, Philipp M. Meyer, Hermann-Josef Gertz, Peter Brust, Henryk Barthel, Swen Hesse

      Pages 255-269

   5. Neuroimaging Findings in Mild Cognitive Impairment

      • Flavio Nobili, Dario Arnaldi, Luca Roccatagliata, Andrea Chincarini, Jennifer Accardo, Agnese Picco et al.

      Pages 271-307

   6. Impact of the IWG/Dubois Criteria for Alzheimer’s Disease in Imaging Studies

      • Bruno Dubois, Olga Uspenskaya

      Pages 309-322

   7. Perfusion SPECT: Its Role in the Diagnosis and Differential Diagnosis of Alzheimer’s Disease, with Particular Emphasis on Guidelines

      • Ronald W. J. van Rheenen, Jacoba P. van Amerongen, Andreas Otte, Peter Paul De Deyn, Rudi A. J. O. Dierckx

      Pages 323-337

   8. Nuclear Imaging in Frontotemporal Dementia

      • Fransje E. Reesink, Gilles N. Stormezand, Rudi A. J. O. Dierckx, Peter Paul De Deyn

      Pages 339-357

   9. Parkinson Dementia: PET Findings

      • Nicolaas I. Bohnen, Kirk A. Frey

      Pages 359-372

   10. SPECT/PET Findings in Lewy Body Dementia

       • Rhiannon Ducksbury, Timothy Whitfield, Zuzana Walker

       Pages 373-415

PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.

• Cerebrovascular Disorders
• Dementia
• Epilepsy
• Movement Disorders
• Neurology
• Nuclear Medicine

“Essential reading for all those who are interested to the role of nuclear medicine in neurology, and more generally in neuroimaging. … this voluminous and up to date publication can be regarded as an encyclopaedia that could have a prominent position in the libraries of all departments involved in neurosciences generally, not only in neuroimaging. … Clearly residents and professionals in nuclear medicine, as well as those involved in neuroimaging, will find this book of interest.” (Christian Marsiglia and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 43, 2016)

• Dept. of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

  Rudi A.J.O. Dierckx

• Faculty of Electrical Engineering and Information Technology, University of Applied Sciences Offenburg, Offenburg, Germany

  Andreas Otte

• Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands

  Erik F.J. Vries, Aren Waarde

• Neurology, University Medical Center Groningen, Groningen, The Netherlands

  Klaus L. Leenders

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