New Frontiers of MR-based Techniques in Multiple Sclerosis

1. Front Matter

   Pages I-X

   PDF

2. Introduction

   • M. Filippi, M. Rovaris, G. Comi

   Pages 1-3

3. Cell-Specific Imaging in Pathologic Conditions of the Central Nervous System, with Special Reference to Multiple Sclerosis

   • V. Dousset, B. Brochet, J.-M. Caille, K. G. Petry

   Pages 5-10

4. Magnetization Transfer Imaging

   • M. Rovaris, M. Filippi

   Pages 11-32

5. Diffusion-Weighted MRI

   • M. Filippi, M. A. Rocca

   Pages 33-45

6. Global Brain Proton MR Spectroscopy in MS

   • O. Gonen, R. I. Grossman

   Pages 47-71

7. Perfusion MRI

   • W. Rashid, D. H. Miller

   Pages 73-82

8. Functional MRI

   • M. Filippi, M. A. Rocca

   Pages 83-97

9. In vivo Microscopic Imaging of Multiple Sclerosis with High Field MRI

   • A. Kangarlu, K. W. Rammohan, E. C. Bourekas, D. W. Chakeres

   Pages 99-104

10. Back Matter

    Pages 105-107

    PDF

In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.

• MRI
• Nervous System
• Proton magnetic resonance spectroscopy
• diffusion-weighted MRI
• magnetization transfer MRI
• multiple sclerosis
• Diagnostic Radiology

• Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University, Ospedale San Raffaele, Milan, Italy

  Massimo Filippi

• Department of Neurology, Scientific Institute and University, Ospedale San Raffaele, Milan, Italy

  Giancarlo Comi

Policies and ethics