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"This book is to ‘provide a complete and up-to-date overview of the technical, methodological, and clinical issues related to the application of MR imaging in MS trials of neurodegeneration.’ … the strength of this compact book would be its value as a compilation of material that is not so much novel as it is difficult to find in a single volume. … It will provide a convenient reference resource for MS investigators interested in the current status of neurodegeneration imaging studies in MS … ." (American Journal of Neuroradiology, Vol. 29, October, 2008)