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Immunology and Alzheimer’s Diseasee

Colloque Medecine et Recherche 1. Meeting Angers 1987

  • Conference proceedings
  • © 1988

Overview

Editors:
  1. Annick Pouplard-Barthelaix

    1. Unité de Neuro-Immunologie et Neuropathologie et INSERM U. 298, C.H.R.U, Angers Cedex, France

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  2. Jean Emile

    1. Service de Neurologie, C.H.R.U, Angers Cedex, France

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  3. Yves Christen

    1. Fondation IPSEN pour la Recherche Thérapeutique, Paris Cedex, France

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Part of the book series: Research and Perspectives in Alzheimer's Disease (ALZHEIMER)

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Table of contents (11 papers)

  1. Front Matter

    Pages I-XII
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  2. Alzheimer’s Disease, a Cerebral Form of Amyloidosis

    • H. M. Wisniewski, J. R. Currie, M. Barcikowska, N. K. Robakis, D. L. Miller
    Pages 1-6

  3. Immunological Markers and Neuropathological Lesions in Alzheimer’s Disease

    • A. Pouplard-Barthelaix
    Pages 7-16

  4. Presence of Immunoglobulins and Complements in the Amyloid Plaques in the Brain of Patients with Alzheimer’s Disease

    • T. Ishii, S. Haga, F. Kametani
    Pages 17-29

  5. The Blood-Brain Barrier in Cerebral Amyloidogenesis in Alzheimer’s Disease and Scrapie

    • P. Eikelenboom, H. Fraser, J. M. Rozemuller, F. C. Stam
    Pages 30-41

  6. Ultrastructural Study of Senile Plaques and Microvessels in the Brain in Alzheimer’s Disease

    • T. Miyakawa
    Pages 42-54

  7. Paired Helical Filaments in Alzheimer’s Disease: Their Formation and Transformation

    • A. Delacourte, A. Defossez
    Pages 55-67

  8. Amyloidosis in the Genesis of Alzheimer’s Disease

    • G. G. Glenner
    Pages 68-75

  9. Protein Chemical and Molecular Biological Studies of Amyloid Precursor Proteins in Alzheimer’s Disease

    • D. J. Selkoe
    Pages 76-87

  10. The Molecular Basis of Cerebral Amyloidosis in Alzheimer’s Disease and the Unconventional Virus Diseases

    • C. L. Masters, R. Martins, G. Simms, B. Rumble, S. Fuller, L. Hutchinson et al.
    Pages 88-95

  11. Genetics, Expression and Localization of the Amyloid Precursor of Alzheimer’s Disease

    • K. Beyreuther, J. M. Salbaum, T. Dyrks, A. Genthe, A. Weidemann, C. Hilbich et al.
    Pages 96-97

  12. Immunodiagnosis and Immunotherapy of Patients with Alzheimer’s Syndrome

    • H. H. Fudenberg, V. K. Singh
    Pages 98-107

  13. Back Matter

    Pages 109-110
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Keywords

About this book

Alzheimer's disease is one of the major scientific, medical and social challenges of our time. This book, the first in the new series Research and Perspectives in Alzheimer's Disease, presents a particularly up-to-date approach of immunological and biochemical aspects. It is written by the most outstanding scientists and contains recent data. The following are among the most interesting ideas contained in this book: - Alzheimer's disease is a cerebral form of amyloidosis. - some data are in accordance with an immunological hypothesis of this disease. - degeneration of microvessels - including amyloid angiopathy - could be very important in the changes in the brain with Alzheimer's disease. - the molecular study of A4 protein and its precursor is important for the understanding of the disease. This synthesis by prominent scientists provides a stimulating hypothesis about the determinism of the disease.

Editors and Affiliations

  • Unité de Neuro-Immunologie et Neuropathologie et INSERM U. 298, C.H.R.U, Angers Cedex, France

    Annick Pouplard-Barthelaix

  • Service de Neurologie, C.H.R.U, Angers Cedex, France

    Jean Emile

  • Fondation IPSEN pour la Recherche Thérapeutique, Paris Cedex, France

    Yves Christen

Bibliographic Information

  • Book Title: Immunology and Alzheimer’s Diseasee

  • Book Subtitle: Colloque Medecine et Recherche 1. Meeting Angers 1987

  • Editors: Annick Pouplard-Barthelaix, Jean Emile, Yves Christen

  • Series Title: Research and Perspectives in Alzheimer's Disease

  • DOI: https://doi.org/10.1007/978-3-642-46634-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-3-642-46636-6Published: 01 March 2012

  • eBook ISBN: 978-3-642-46634-2Published: 08 March 2013

  • Series ISSN: 0945-6066

  • Series E-ISSN: 2196-310X

  • Edition Number: 1

  • Number of Pages: XII, 110

  • Topics: Neurology, Allergology, Immunology

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