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  • © 2010

The Dopamine Receptors

Editors:

  • Relies heavily on new knowledge
  • The use of knock-out mice and subtype-selective drugs merit discussion in stand-alone chapters
  • The field of G protein-coupled receptors has advanced significantly since the publication of the first edition, with a model of GPCR signaling based on linear, compartmentalized pathways having been replaced by a more complex, richer model in which neurotransmitter effects are mediated by a signalplex composed of numerous signaling proteins, including multiple GPCRs, other types of receptors, such as ionotropic receptors, accessory and scaffolding proteins, and effectors
  • Key aspects of this advanced model are specifically addressed in new chapters on dopamine receptor-interacting proteins and on dopamine receptor oligomerization
  • Includes supplementary material: sn.pub/extras

Part of the book series: The Receptors (REC)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xii
  2. Gene and Promoter Structures of the Dopamine Receptors

    • Ursula M. D’Souza
    Pages 23-46
  3. Structural Basis of Dopamine Receptor Activation

    • Irina S. Moreira, Lei Shi, Zachary Freyberg, Spencer S. Ericksen, Harel Weinstein, Jonathan A. Javitch
    Pages 47-73
  4. Dopamine Receptor Subtype-Selective Drugs: D2-Like Receptors

    • Olaf Prante, Miriam Dörfler, Peter Gmeiner
    Pages 101-135
  5. Dopamine Receptor Signaling: Intracellular Pathways to Behavior

    • Robert J. Romanelli, John T. Williams, Kim A. Neve
    Pages 137-173
  6. Regulation of Dopamine Receptor Trafficking and Responsiveness

    • Melissa L. Perreault, Vaneeta Verma, Brian F. O’Dowd, Susan R. George
    Pages 193-217
  7. Dopamine Receptor-Interacting Proteins

    • Lisa A. Hazelwood, R. Benjamin Free, David R. Sibley
    Pages 219-254
  8. Dopamine Receptor Oligomerization

    • Kjell Fuxe, Daniel Marcellino, Diego Guidolin, Amina Woods, Luigi Agnati
    Pages 255-280
  9. Dopamine Receptor Modulation of Glutamatergic Neurotransmission

    • Carlos Cepeda, VĂ©ronique M. AndrĂ©, Emily L. Jocoy, Michael S. Levine
    Pages 281-302
  10. Unraveling the Role of Dopamine Receptors In Vivo: Lessons from Knockout Mice

    • Emanuele Tirotta, Claudia De Mei, Chisato Iitaka, Maria Ramos, Dawn Holmes, Emiliana Borrelli
    Pages 303-322
  11. Dopamine Receptors and Behavior: From Psychopharmacology to Mutant Models

    • Gerard J. O’Sullivan, Colm O’Tuathaigh, Katsunori Tomiyama, Noriaki Koshikawa, John L. Waddington
    Pages 323-371
  12. Dopamine Modulation of the Prefrontal Cortex and Cognitive Function

    • Jeremy K. Seamans, Trevor W. Robbins
    Pages 373-398
  13. In Vivo Imaging of Dopamine Receptors

    • Anissa Abi-Dargham, Marc Laruelle
    Pages 399-430
  14. Dopamine Receptors and the Treatment of Schizophrenia

    • Nathalie Ginovart, Shitij Kapur
    Pages 431-477
  15. Dopamine Receptors and the Treatment of Parkinson’s Disease

    • Eugenia V. Gurevich, Vsevolod V. Gurevich
    Pages 525-584
  16. Dopamine Receptor Genetics in Neuropsychiatric Disorders

    • Frankie H.F. Lee, Albert H.C. Wong
    Pages 585-632

About this book

As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.

Reviews

...extremely well-written and thoroughly referenced... All neuroscientists searching for an invaluable reference which provides a clearer understanding of the dopamine field and its future direction should have this book at their fingertips. -Journal of Medicinal Chemistry

Editors and Affiliations

  • Portland VA Medical Center (R & D-30), Portland, U.S.A.

    Kim A. Neve

Bibliographic Information

Buy it now

Buying options

eBook USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access