Textbook of Neuromodulation

1. Front Matter

   Pages i-xiii

   PDF

2. Basic Aspects

   1. Front Matter

      Pages 1-1

      PDF

   2. Principles of Neuromodulation

      • Veronika M. Stock, Helena Knotkova, Michael A. Nitsche

      Pages 3-6

   3. Methods and Technologies for Low-Intensity Transcranial Electrical Stimulation: Waveforms, Terminology, and Historical Notes

      • Berkan Guleyupoglu, Pedro Schestatsky, Felipe Fregni, Marom Bikson

      Pages 7-16

3. Methods

   1. Front Matter

      Pages 17-17

      PDF

   2. Peripheral Nerve Stimulation

      • Konstantin V. Slavin, Alexios G. Carayannopoulos, Mark Plazier, Sven Vanneste, Dirk De Ridder

      Pages 19-33

   3. Spinal Cord Stimulation

      • Kliment Gatzinsky

      Pages 35-52

   4. Dorsal Root Ganglion Stimulation: A Target for Neuromodulation Therapies

      • A. Liong Liem, Imre Poldino Krabbenbos, Jeffery Kramer

      Pages 53-59

   5. Deep Brain Stimulation

      • Volker M. Tronnier, Dirk Rasche

      Pages 61-72

   6. Motor Cortex Stimulation

      • Dirk Rasche, Volker M. Tronnier

      Pages 73-85

   7. Physiological Basis of Transcranial Magnetic Stimulation

      • Anne P. Caruso, Monica A. Perez

      Pages 87-99

   8. Transcranial Direct Current Stimulation: Protocols and Physiological Mechanisms of Action

      • Michael A. Nitsche, Min-Fang Kuo, Walter Paulus, Andrea Antal

      Pages 101-111

   9. A Role of Computational Modeling in Customization of Transcranial Direct Current Stimulation for Susceptible Populations

      • Dennis Truong, Preet Minhas, Albert Mokrejs, Marom Bikson

      Pages 113-126

   10. Cranial Electrical Stimulation

       • Janet Mindes, Marc J. Dubin, Margaret Altemus

       Pages 127-150

   11. The Mechanisms and Actions of Motor Imagery Within the Clinical Setting

       • Nicola E. Walsh, Louise Jones, Candida S. McCabe

       Pages 151-158

   12. Neuroprosthesis and Sensorimotor Training

       • Martin Diers

       Pages 159-167

4. Clinical Potential and Applications

   1. Front Matter

      Pages 169-169

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   2. Clinical Applications of Neuromodulation in Psychiatry

      • Pedro Shiozawa, Rosamaria Raza, Quirino Cordeiro Jr., André Russowsky Brunoni

      Pages 171-185

   3. Applications of Neuromodulation in Pain Management

      • Helena Knotkova, Aaron Greenberg, Eliezer Soto, Ricardo A. Cruciani

      Pages 187-210

   4. Applications of Neuromodulation in Neurology and Neurorehabilitation

      • Nam-Jong Paik

      Pages 211-245

Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.

• invasive approaches, stimulation therapies
• nervous system, peripheral nerve stimulation,
• neuromodulaiton, neuroimaging, neuroplasticity
• non-invasive approaches
• psychiatry, pain management, neurorehabiliation

“Written and edited by recognized clinician-researchers in the field, this is a welcome addition to the neuropsychiatric literature. … This is an excellent and well-written book on neuromodulation. Anyone who wishes to learn about this important field would want to start out with this. I highly recommend it.” (Michael Joel Schrift, Doody's Book Reviews, May, 2015)

“This is a monumental comprehensive book on the diagnostic and therapeutic approaches in neurological & Psychiatric illnesses. … Psychopharmacologists, neurologists, neurosurgeons, inc. residents, fellows and seasoned practitioners in Psychiatry will all find this text very useful in practice, especially when comparing drug with implant technology. A very good series concerning back pain, chronic headaches, inc. occipital neuralgia, trigeminal disorders, cluster, headaches (HC), and migraines and their treatments are used well here.” (Joseph J. Grenier, Amazon.com, March, 2015)

• Institute for Innovation in Palliative Care, Metropolitan Jewish Health Systems (MJHS), New York, USA

  Helena Knotkova

• University of Lübeck, Department of Neurosurgery University Hospital of Schleswig-Holstein, Lübeck, Germany

  Dirk Rasche

Helena Knotkova, PhD is Co-Chief of the Research Division, Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, New York and Co-founder as well as Director of Research at Institute of Non-invasive Brain Stimulation of New York, and Assistant Professor of Neurology, Albert Einstein College of Medicine, Bronx, New York. She is a co-founder of the Special Interest Group on Neuromodulation under the International Association for the Study of Pain (IASP). Dirk Rasche, MD is a general Neurosurgeon and Assistant Professor of Neurosurgery, Department of Neurosurgery, University of Lübeck, Germany. Dr. Rasche is as an active member of IASP, EFIC, INS and multiple other international and national associations.

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