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  • © 2013

Antiepileptic Drug Interactions

A Clinical Guide

Authors:

  • Covers all clinically licensed AEDs, including those licensed only in specific countries or that have limited indications; these are presented in alphabetical order for ease of reference

  • Three separate sections highlight the way AED interactions occur to assist the reader in quickly and easily locating any potential interactions for specific drug classes

  • Includes details of the mechanism and magnitude of the interaction to inform the reader to anticipate the clinical significance of the drug interaction and thus allow for appropriate and timely dose adjustment to minimize the consequence of the interaction

  • Includes supplementary material: sn.pub/extras

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Table of contents (64 chapters)

  1. Front Matter

    Pages i-lxv
  2. Drug Interactions Between AEDs

    1. Front Matter

      Pages 1-3
    2. Acetazolamide

      • P. N. Patsalos
      Pages 5-9
    3. Carbamazepine

      • P. N. Patsalos
      Pages 11-21
    4. Clobazam

      • P. N. Patsalos
      Pages 23-28
    5. Clonazepam

      • P. N. Patsalos
      Pages 29-34
    6. Eslicarbazepine Acetate

      • P. N. Patsalos
      Pages 35-40
    7. Ethosuximide

      • P. N. Patsalos
      Pages 41-46
    8. Felbamate

      • P. N. Patsalos
      Pages 47-52
    9. Gabapentin

      • P. N. Patsalos
      Pages 53-57
    10. Lacosamide

      • P. N. Patsalos
      Pages 59-64
    11. Lamotrigine

      • P. N. Patsalos
      Pages 65-73
    12. Levetiracetam

      • P. N. Patsalos
      Pages 75-80
    13. Methsuximide

      • P. N. Patsalos
      Pages 81-85
    14. Oxcarbazepine

      • P. N. Patsalos
      Pages 87-93
    15. Phenobarbital

      • P. N. Patsalos
      Pages 95-102
    16. Phenytoin

      • P. N. Patsalos
      Pages 103-111
    17. Piracetam

      • P. N. Patsalos
      Pages 113-117
    18. Pregabalin

      • P. N. Patsalos
      Pages 119-123
    19. Primidone

      • P. N. Patsalos
      Pages 125-131

About this book

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs.

 

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.

Authors and Affiliations

  • Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom

    P. N. Patsalos

About the author

Philip N. Patsalos is a Consultant Clinical Pharmacologist, a Professor of Clinical Pharmacology and Head of Pharmacology and Therapeutics at the Institute of Neurology - University College London, at the National Hospital for Neurology and Neurosurgery, Queen Square and at the Epilepsy Society, Chalfont St Peter, UK.

Professor Patsalos’ clinical and research interests relate to the therapeutics of epilepsy and include: new drug treatments and strategies, new drug development (Phase II and III trials) and formulations, pharmacokinetic profiling and drug interactions. He has in excess of 200 publications (books, book chapters and peer reviewed papers) and has served on various International League Against Epilepsy committees including the Commission on Therapeutic Strategies, the Sub-Commission on Polytherapy and Drug Interaction and the Sub-Commission on Therapeutic Drug Monitoring.

He is presently an Editorial Board member of numerous journals including Drugs, Epilepsy Research and Treatment, European Neurology Journal, Expert Opinion on Emerging Drugs, Expert Review of Clinical Pharmacology and Therapeutic Drug Monitoring. He is also Associate Editor of Epilepsia and of the journal Epileptologia.

Bibliographic Information

  • Book Title: Antiepileptic Drug Interactions

  • Book Subtitle: A Clinical Guide

  • Authors: P. N. Patsalos

  • DOI: https://doi.org/10.1007/978-1-4471-2434-4

  • Publisher: Springer London

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag London 2013

  • eBook ISBN: 978-1-4471-2434-4Published: 03 December 2012

  • Edition Number: 2

  • Number of Pages: LXV, 437

  • Number of Illustrations: 29 b/w illustrations

  • Topics: Neurology, Psychopharmacology

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access