Logo - springer
Slogan - springer

Medicine - Neurology | Highly Selective Neurotoxins - Basic and Clinical Applications

Highly Selective Neurotoxins

Basic and Clinical Applications

Kostrzewa, Richard (Ed.)

1998, XII, 404 p.

A product of Humana Press
Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$199.00

(net) price for USA

ISBN 978-1-59259-477-1

digitally watermarked, no DRM

Included Format: PDF

download immediately after purchase


learn more about Springer eBooks

add to marked items

Hardcover
Information

Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$249.00

(net) price for USA

ISBN 978-0-89603-465-5

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

Softcover
Information

Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$249.00

(net) price for USA

ISBN 978-1-61737-047-2

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

  • About this book

In Highly Selective Neurotoxins, experienced experimentalists critically review and evaluate the most common and important neurotoxins used today to precisely destroy selected neurons. Each informative chapter thoroughly describes the significant mechanisms of action of a neurotoxin, as well as fully discussing the limits on its use and its clinical applicability. Several clinically oriented chapters are significant for neurologists treating Parkinsonism, for psychiatrists treating drug abuse and neurodegenerative disorders, and for primary care physicians treating patients with appetite suppressants.

Highly Selective Neurotoxins provides all the basic knowledge needed to obtain a predictable experimental outcome with these neurotoxins. Its authoritative coverage of the newest findings on experimentally important neurotoxins makes their proper use and their limitations clear and practical from both experimental and theoretical points of view.







Content Level » Research

Keywords » Neuroscience - Parkinson - amphetamine - catecholamines - cocaine - dopamine - neural mechanisms - neurons - neurotoxicity

Related subjects » Neurology - Neuroscience

Table of contents 

6-Hydroxydopamine and Related Catecholaminergic Neurotoxins: Molecular Mechanisms, C. L. Blank, R. J. Lewis, and R. E. Lehr. The Use of Neurotoxins to Lesion Catecholamine-Containing Neurons to Model Clinical Disorders: Approach for Defining Adaptive Neural Mechanisms and Role of Neurotrophic Factors in Brain, C. R. Breese and G. R. Breese. 6-Hydroxydopamine as a Tool for Studying Catecholamines in Adult Animals: Lessons from the Neostriatum, M. J. Zigmond and K. A. Keefe. 6-Hydroxydopa, a Catecholamine Neurotoxin and Endogenous Excitotoxin at Non-NMDA Receptors, R. M. Kostrzewa. 2-Chloroethylamines (DSP4 and Xylamine): Toxic Actions on Noradrenergic Neurons, G. Jaim-Etcheverry. MPTP: A Dopaminergic Neurotoxin, J. E. Royland and J. W. Langston. Haloperidol-Derived Pyridinium Metabolites: Structural and Toxicological Relationships to MPP+-Like Neurotoxins, C. J. Van der Schyf, E. Usuki, S. M. Pond, and N. Castagnoli, Jr. The Neurotoxic Effects of Continuous Cocaine and Amphetamine in Habenula, G. Ellison. Evidence for and Mechanism of Action of Neurotoxicity of Amphetamine Related Compounds, R. Lew, J. E. Malberg, G. A. Ricuarte, and L. S. Seiden. Molecular Mechanisms of Action of 5,6- and 5,7-Dihydroxytryptamine, T. Tabatabaie and G. Dryhurst. Use of 5,6- and 5,7-Dihydroxytryptamine to Lesion Serotonin Neurons, M. R. Pranzatelli. Selective Cholinergic Neurotoxins: AF64A and 192-IgG-Saporin, T. J. Walsh and P. E. Potter. Glutamatergic Receptor Agonists and Brain Pathology, E. M. Urbanska, A. Dekundy, Z. Kleinrok, W. A. Turski, and S. J. Czuczwar. Neurotoxicity of NMDA Receptor Antagonists, S. Rajdev and F. R. Sharp. Toxic Vanilloids, A. Szallasi. Index.

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Neurology.