The Basal Ganglia VI

1. Front Matter

   Pages i-xvii

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2. Studies in Humans

   1. Front Matter

      Pages 1-1

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   2. What has Stereotactic Surgery Taught us about Basal Ganglia Function?

      • David J. Brooks

      Pages 3-14

   3. Pathophysiology of the Internal Segment of the Globus Pallidus in Parkinson’s Disease

      • Andres M. Lozano, William D. Hutchison, Ron Levy, Anthony E. Lang, Jonathan O. Dostrovsky

      Pages 15-21

   4. Apomorphine Responses in Globus Pallidus and Subthalamus of Parkinsonian Patients Undergoing Stereotaxic Neurosurgery: Lack of Evidence for the So-Called Indirect Pathway

      • A. Stefani, A. Bassi, A. Peppe, M. Pierantozzi, S. Frasca, L. Brusa et al.

      Pages 23-31

   5. Neuronal Activity of GPe in Parkinson’s Disease

      • Chihiro Ohye, Masafumi Hirato, Akio Takahashi, Katsushige Watanabe

      Pages 33-41

   6. Acute Effects of Levodopa and Pallidotomy on Bimanual Repetitive Arm Movements in Patients with Parkinson’s Disease

      • R. Levy, W. D. Hutchison, A. E. Lang, A. M. Lozano, J. O. Dostrovsky

      Pages 43-50

   7. Tremor in Parkinson’s Disease

      • Anne Beuter, Roderick Edwards

      Pages 51-60

   8. Visuo-Spatial Attention in Non-Demented Patients with Parkinson’s Disease

      • Constantin Potagas, Nguyen Bathien, André Hugelin

      Pages 61-81

   9. Neuronal Intranuclear Inclusions in Neostriatal Striosomes and Matrix in Huntington’s Disease

      • John C. Hedreen

      Pages 83-86

   10. Probing Striatal Function in Obsessive Compulsive Disorder

       • Scott L. Rauch

       Pages 87-93

3. Animal Models

   1. Front Matter

      Pages 95-95

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   2. Evolution of the Multiunit Activity of the Basal Ganglia in the Course of Dynamic Experimental Parkinsonism

      • Erwan Bezard, Thomas Boraud, Bernard Bioulac, Christian E. Gross

      Pages 97-106

   3. Evidence for Neuronal Dysfunction in a Mouse Model of Early Stages of Huntington’s Disease

      • M.-F. Chesselet, M. S. Levine, C. Cepeda, L. Menalled, H. Zanjani

      Pages 107-115

   4. Effects of GDNF on Nigrostriatal Dopamine Neurons

      • Carl Rosenblad, Deniz Kirik, Anders Björklund

      Pages 117-130

   5. A Role for the Vesicular Monoamine Transporter (VMAT2) in Parkinson’s Disease

      • Dwight C. German, Patricia K. Sonsalla

      Pages 131-137

   6. Quantitative Analysis and Behavioural Correlates of Lesioning of the Subthalamic Nucleus in the Hemiparkinsonian Marmoset

      • J. M. Henderson, L. E. Annett, E. M. Torres, S. B. Dunnett

      Pages 139-149

   7. Effects of Reversible Blockade of Pedunculopontine Tegmental Nucleus on Voluntary Arm Movement in Monkey

      • Masaru Matsumura, Katsushige Watanabe

      Pages 151-158

   8. Differential Reductions in Dopaminergic Innervation of the Motor-Related Areas of the Frontal Lobe in MPTP-Treated Monkeys

      • Yoshio Yamaji, Masaru Matsumura, Jun Kojima, Hironobu Tokuno, Atsushi Nambu, Masahiko Inase et al.

      Pages 159-167

   9. Control of Epileptic Seizures

      • Colin Deransart, Véronique Riban, Laurent Vercueil, Karine Nail-Boucherie, Christian Marescaux, Antoine Depaulis

      Pages 169-178

This volume, the sixth in the IBAGS series, summarizes major contributions in clinical and basic research on the basal ganglia. The sixth meeting of the Society was held on Cape Cod, in the state of Massachusetts, USA, in October, 1998. Altogether 16 countries were represented by 227 participants. This volume contains papers contributed by participants. The focus of the sixth triennial IBAGS meeting, and of this volume, was to bring to­ gether leaders in basic and clinical science to address two sets of still-persisting questions in the field. The first set focuses on the functions of the basal ganglia in health and disease: What are the core functions of the basal ganglia and cortico-basal ganglia loops? How are these core functions disrupted in disorders affecting the basal ganglia? How do we account for the broad range of behaviors affected by basal ganglia disorders and for the increasing evidence that the basal ganglia influence cognitive as well as motor functions? These issues are addressed in the first five sections of the current volume, which summarize advances in the study of basal ganglia disorders based on studies in humans (Section 1), new results obtained with experimental animal models of basal ganglia disorders (Section 2), results of experiments on information coding in the basal ganglia (Section 3) and new information about functions of the basal ganglia related to learning and adaptive motor control (Section 4).

• Neuroscience
• Parkinson
• anatomy
• dopamine
• evolution
• neural mechanisms
• neurons
• neurophysiology
• neurosurgery
• pathophysiology
• physiology

• Massachusetts Institute of Technology, Cambridge, USA

  Ann M. Graybiel

• Emory University, Atlanta, USA

  Mahlon R. Delong

• University of Tennessee Memphis, Memphis, USA

  Stephen T. Kitai

Policies and ethics