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Late Graft Loss

Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996

  • Conference proceedings
  • © 1997

Overview

Part of the book series: Transplantation and Clinical Immunology (TRAC, volume 28)

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Table of contents (58 papers)

  1. Incidence and modalities

  2. Immunological factors

  3. Non-immunological factors

  4. Prevention and treatment

Keywords

About this book

In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years.
Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration.

Editors and Affiliations

  • Hospital Edouard Herriot, Lyon 3, France

    J. M. Dubernard

Bibliographic Information

  • Book Title: Late Graft Loss

  • Book Subtitle: Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996

  • Editors: J. L. Touraine, J. Traeger, H. Bétuel, J. M. Dubernard, J. P. Revillard, C. Dupuy

  • Series Title: Transplantation and Clinical Immunology

  • DOI: https://doi.org/10.1007/978-94-011-5434-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1997

  • Hardcover ISBN: 978-0-7923-4315-8Published: 31 January 1997

  • Softcover ISBN: 978-94-010-6286-2Published: 29 October 2012

  • eBook ISBN: 978-94-011-5434-5Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 239

  • Topics: Nephrology, Transplant Surgery, Immunology

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