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  • Conference proceedings
  • © 1997

Late Graft Loss

Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996

Part of the book series: Transplantation and Clinical Immunology (TRAC, volume 28)

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Table of contents (58 papers)

  1. Front Matter

    Pages i-xvi
  2. Incidence and modalities

    1. Front Matter

      Pages 1-1
    2. Histopathology of chronic rejection

      • Richard K. Sibley
      Pages 13-23
    3. Evaluation of biopsy changes in the early diagnosis of chronic transplant nephropathy

      • D. Serón, F. Moreso, J. Bover, E. Condom, X. Fulladosa, S. Gil-Vernet et al.
      Pages 25-30
    4. Is there any relationship between the early glomerular filtration rate and late graft dysfunction in renal transplantation?

      • C. Pouteil-Noble, L. Remontet, M. Lombardo, J. L. Touraine, A. Hadj-Aissa, N. Pozet
      Pages 31-37
    5. Transplantation atherosclerosis: Definition and pathogenesis

      • Bengt Fellström, Ulla Backman, Levent Akyürek, Erik Larsson, Lilja Zezina
      Pages 39-48
  3. Immunological factors

    1. Front Matter

      Pages 49-49
    2. Immunological mechanism of chronic rejection

      • Leendert C. Paul, Jagadeesan Muralidharan, Syed A. Muzaffar, Jean-François Valentin
      Pages 51-61
    3. The role of adhesion molecules in chronic rejection

      • Uwe W. Heemann, Andreas Kribben, Raphael Schäfers, Thomas Philipp
      Pages 63-67
    4. A role for TH2 cells in chronic allograft rejection?

      • Michel Goldman, Hans-Dieter Volk
      Pages 69-73
    5. Treatment of refractory acute allograft rejection with aerosolized cyclosporin in lung transplant recipients

      • Robert J. Keenan, Aldo Iacono, James H. Dauber, Gerald C. Smaldone, Bartley P. Griffith
      Pages 75-76
    6. Ischemia—reperfusion injury as a risk factor for late kidney graft failure

      • J. M. Grinyó, S. Gil-Vernet, F. Moreso, D. Serón, X. Fulladosa, J. M. Cruzado et al.
      Pages 77-83
  4. Non-immunological factors

    1. Front Matter

      Pages 91-91
    2. Nephron endowment and the pathogenesis of chronic renal failure

      • Barry M. Brenner, Harald S. Mackenzie
      Pages 93-100
    3. Are child donors better than adult donors for pediatric kidney recipients?

      • U. B. Berg, L. Dubourg, A.-B. Bohlin, A. Hadj-Aïssa, G. Tydén, P. Cochat
      Pages 101-103
    4. Late graft loss in combined kidney-pancreas transplantation

      • L. C. Feitosa Tajra, M. Benchaid, X. Martin, M. Dawahra, N. Lefrançois, J. L. Touraine et al.
      Pages 105-108
  5. Prevention and treatment

    1. Front Matter

      Pages 109-109

About this book

In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years.
Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration.

Editors and Affiliations

  • Hospital Edouard Herriot, Lyon 3, France

    J. M. Dubernard

Bibliographic Information

  • Book Title: Late Graft Loss

  • Book Subtitle: Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996

  • Editors: J. L. Touraine, J. Traeger, H. Bétuel, J. M. Dubernard, J. P. Revillard, C. Dupuy

  • Series Title: Transplantation and Clinical Immunology

  • DOI: https://doi.org/10.1007/978-94-011-5434-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1997

  • Hardcover ISBN: 978-0-7923-4315-8Published: 31 January 1997

  • Softcover ISBN: 978-94-010-6286-2Published: 29 October 2012

  • eBook ISBN: 978-94-011-5434-5Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 239

  • Topics: Nephrology, Transplant Surgery, Immunology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access