Basics of Respiratory Mechanics and Artificial Ventilation

1. Front Matter

   Pages I-XI

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2. Basics of Respiratory Mechanics

   1. Front Matter

      Pages 1-1

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   2. Principles of measurement of respiratory mechanics

      • W. A. Zin

      Pages 3-8

   3. Statics of the respiratory system

      • E. D’Angelo

      Pages 9-19

   4. Respiratory mechanics during general anaesthesia in healthy subjects

      • P. Pelosi, M. Resta, L. Brazzi

      Pages 21-35

   5. Resistance measurements. Forced oscillations and plethysmography

      • R. Peslin

      Pages 37-57

   6. Oscillatory mechanics: principles and clinical applications

      • U. Lucangelo

      Pages 59-80

   7. Resistance measurement in ventilator-dependent patients

      • A. Rossi

      Pages 81-85

   8. Mechanical models of the respiratory system: linear models

      • W. A. Zin, R. F. M. Gomes

      Pages 87-94

   9. Mechanical models of the respiratory system: non-linear and inhomogeneous models

      • Z. Hantos

      Pages 95-107

   10. Mechanical implications of viscoelasticity

       • J. Milic-Emili, E. D’Angelo

       Pages 109-118

   11. Alveolar micromechanics

       • P. V. Romero

       Pages 119-131

   12. Partitioning of lung responses into airway and tissue components

       • M. S. Ludwig

       Pages 133-142

3. The Work of the Respiratory System

   1. Front Matter

      Pages 143-143

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   2. How the diaphragm works in normal subjects

      • N. B. Pride

      Pages 145-152

   3. How the diaphragm works in respiratory disease

      • N. B. Pride

      Pages 153-159

   4. Evaluation of the inspiratory muscle mechanical activity during Pressure Support Ventilation

      • M. C. Olivei, C. Galbusera, M. Zanierato, G. Iotti

      Pages 161-164

   5. Work of breathing

      • J. Milic-Emili, E. Rocca, E. D’Angelo

      Pages 165-175

4. Artificial Ventilation — Principles, Techniques, Clinical Applications

   1. Front Matter

      Pages 177-177

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   2. Respiratory mechanics in ARDS

      • P. Pelosi, M. Resta, L. Gattinoni

      Pages 179-189

Management of the intensive care patient afflicted by respiratory insufficiency requires knowledge of the pathophysiological basis for altered functions. The etiology and therapy of pulmonary diseases, such as acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD) are highly complex. While physiologists and pathophysiologists work prevalently with theoretical modes, clinicians employ sophisticated ventilation support technologies in the attempt to understand the pathophysiological mechanisms of the pulmonary diseases which can present with varying grades of severity. Despite the availability of advanced technologies it is common to personalize the treatment protocol according to the patient's physiologic structure.Given the complexity and difficulties of treating respiratory disease, a strong collaboration between clinicians and physiologists is of fundamtental importance.

• Atmen
• PEEP
• Respiratory systems
• anesthesia and respiratory mechanisms
• diaphragm
• gas exchange
• intensive care medicine
• mechanical ventilation
• muscle fatigue
• non-invasiv e ventilation
• pathophysiology
• physiology
• tissue
• viso-elastic properties
• wor

• Meakins-Christie Laboratories, McGill University, Montreal, Canada

  J. Milic-Emili

• Department of Anaesthesia, Intensive Care and Pain Therapy, University of Trieste, Cattinara Hospital, Italy

  U. Lucangelo

• Department of Anaesthesia and Intensive Care, New S. Gerardo Hospital, Monza, Italy

  A. Pesenti

• Department of Biophysic “Carlos Chagas Filho” Laboratory of Respiratory Physiology, Federal University of Rio de Janeiro, Brazil

  W. A. Zin

Policies and ethics