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Antiphospholipid Antibody Syndrome

From Bench to Bedside

  • Book
  • © 2015

Overview

Editors:
  1. Pier Luigi Meroni

    1. Department of Rheumatology, Gaetano Pini Institute, Milan, Italy

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  • Provides up-to-date knowledge on the pathogenesis and management of the syndrome
  • Presents and discusses innovative treatments in addition to standard treatment options
  • Describes the involvement of other organs or organ systems

Part of the book series: Rare Diseases of the Immune System (RDIS, volume 0)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Genetics and Origin of Antiphospholipid Syndrome

    • Alessandra Soriano, Miri Blank, Yehuda Shoenfeld
    Pages 1-12

  3. The Paradox of Lupus Anticoagulant

    • Alessandra Banzato, Vittorio Pengo
    Pages 13-23

  4. Antiphospholipid Antibody Mechanisms of Thrombosis

    • Pier Luigi Meroni, Chiara Crotti, Cecilia Chighizola
    Pages 25-35

  5. The Pathogenic Mechanisms for Antiphospholipid Antibodies (aPL)-Mediated Pregnancy Loss

    • Nicoletta Di Simone, Silvia D’Ippolito
    Pages 37-46

  6. Classification Criteria for the Antiphospholipid Syndrome

    • Ronald H. W. M. Derksen, Ruth Fritsch-Stork
    Pages 47-59

  7. Non-classification Criteria

    • Maria Gerosa, Francesca Rovelli
    Pages 61-74

  8. Obstetric APS

    • Micaela Fredi, Angela Tincani
    Pages 75-87

  9. APS and the Nervous System

    • Cecilia Beatrice Chighizola, Davide Sangalli, Barbara Corrà, Vincenzo Silani, Laura Adobbati
    Pages 89-102

  10. Antiphospholipid Syndrome (APS) and the Renal Involvement

    • Nicoletta Mezzina, Renato Alberto Sinico
    Pages 103-112

  11. Non-Thrombotic Hematologic Manifestations in APS

    • Wilma Barcellini, Carolina Artusi
    Pages 113-126

  12. Heart and APS

    • Gentian Denas, Vittorio Pengo
    Pages 127-150

  13. Skin Involvement in Antiphospholipid Syndrome

    • Angelo Valerio Marzano, Silvia Alberti Violetti, Riccardo Lazzari, Emilio Berti
    Pages 151-161

  14. Additional Organs Involved in Antiphospholipid Syndrome: Eye, Ear-Nose-Throat, Lung, Gastroenteric System, Endocrine Glands

    • Maria De Santis, Angela Ceribelli, Carlo Selmi
    Pages 163-168

  15. Differential Diagnosis

    • Domenico Prisco, Giacomo Emmi, Elena Silvestri, Lucia Ciucciarelli, Elena Niccolai, Mario Milco D’Elios et al.
    Pages 169-184

  16. Treatment of Thrombosis in Antiphospholipid Syndrome

    • Simon Braham, Paolo Bucciarelli, Marco Moia
    Pages 185-192

  17. Treatment of Pregnancy Complications

    • Barbara Acaia, Federica Rossi, Cecilia Beatrice Chighizola
    Pages 193-206

  18. Antiphospholipid Antibody Carriers

    • Francesca Dall’Ara, Cecilia Nalli, Laura Andreoli
    Pages 207-218

  19. New Treatments

    • Cecilia Beatrice Chighizola, Tania Ubiali
    Pages 219-232

  20. Secondary Antiphospholipid Syndrome

    • Anisur Rahman, Maria Gabriella Raimondo
    Pages 233-248
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Keywords

About this book

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Reviews

From the book reviews:

“The purpose is to provide an overview of this very difficult subject that will benefit bench researchers as well as bedside clinicians. The book would serve any audience who wants to know more about antiphospholipid syndrome. … This is an excellent, up-to-date overview of antiphospholipid syndrome. It will serve as a handy tool to get more information on the topic.” (Dany V. Thekkemuriyil, Doody’s Book Reviews, February, 2015)

Editors and Affiliations

  • Department of Rheumatology, Gaetano Pini Institute, Milan, Italy

    Pier Luigi Meroni

Bibliographic Information

  • Book Title: Antiphospholipid Antibody Syndrome

  • Book Subtitle: From Bench to Bedside

  • Editors: Pier Luigi Meroni

  • Series Title: Rare Diseases of the Immune System

  • DOI: https://doi.org/10.1007/978-3-319-11044-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-11043-1Published: 03 December 2014

  • Softcover ISBN: 978-3-319-35710-2Published: 23 August 2016

  • eBook ISBN: 978-3-319-11044-8Published: 20 November 2014

  • Series ISSN: 2282-6505

  • Series E-ISSN: 2283-6403

  • Edition Number: 1

  • Number of Pages: X, 267

  • Number of Illustrations: 4 b/w illustrations, 15 illustrations in colour

  • Topics: Hematology, Rheumatology, Gynecology

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