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Medicine - Internal Medicine | Myelodysplasias - Molecular Pathology and Treatment


Molecular Pathology and Treatment

Mufti, Ghulam J. (Ed.)

2013, Approx. 350 p.

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  • About this book

Content Level » Professional/practitioner

Keywords » Allogenic Stem Cell Transplantation - Aplastic Anemia - Clonal Disorders of Haemopoiesis - Demethylating Agents - Genomic Instability Syndromes - Lenolidamide

Related subjects » Internal Medicine - Oncology & Hematology

Table of contents 

1. Myelodysplastic Syndrome (MDS): How common is it? i.e. epidemiology and risk factors.

E Estey, MD Anderson (soon to move to Fred Hutchinson Cancer

Centre, Seattle).

2. Therapy related myelodysplasia. Predisposing factors and

molecular genetics

J. Pederson-Bjergaard, Denmark.

3. Cytogenetic abnormalities in primary and secondary MDS

D. Haase, Gottingen, Germany

4. The value of SNP and expression profiling in diagnosis and prognosis

Mufti GJ

5. Molecular pathology of 5q-syndrome and 5q- abnormality

Benjamin Ebert, Dana Farber, Boston

6. Genomic instability syndromes and myelodysplasia

Inderjeet Dokal, Barts and The London

7. Animal models of myelodysplasia.

Timothy Graubert, Saint Louis

8. Biological defects of haemopoiesis of low risk MDS

Eva Hellstrom-Lindberg - Sweden

9. Prognostic evaulation of primary MDS

Ulrich Germing, Germany

10. FAB, WHO, IWG and beyond

John Bennett, Rochester

11. Methylation and histone acetylation in the context of MDS

Steve Gore, Johns Hopkins

12. Treatment of MDS with demethylating agents and HDAC inhibitor

Hagop Kantarjian, MD Anderson

13. Supportive treatment in low and high risk MDS

Pierre Fenaux, Paris

14. Allogeneic stem cell transplantation in MDS

Ziyi Lim and Theo De Witte

15. Immune dysregulation and immunosuppressive therapy MDS

Shahram Kordasti, King's College London

16. Aplastic anaemia/MDS overlap syndrome

Neil Young, NIH

17. Clinical and molecular spectrum of Myeloproliferative/Myelodysplastic disorders (MPD/MDS)

Ayalew Tefferi, Mayo Clinic

18. MPD/MDS overlap syndromes

Michael McDevitt

19. Adult and juvenile Chronic Myelomonocytic Leukemia (CMML)

Christine Neimyer and _ Steenma



20. Emerging therapies including Lenolidamide

Alan List, Tampa, Florida

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