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  • © 2011

Myeloproliferative Neoplasms

Biology and Therapy

  • Provides the most up-to-date data on myeloproliferative neoplasms
  • Explores the role of JAK2 and MPL mutations in pathogenesis and treatment
  • Gives succinct, practical coverage of conventional and investigational therapies, including transplant
  • Covers current classification and WHO-based diagnostic criterion
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Hematology (CH)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
  2. Genetics of the Myeloproliferative Neoplasms

    • Omar Abdel-Wahab, Ross L. Levine
    Pages 39-68
  3. Cytogenetic Findings in Classical MPNs

    • John T. Reilly
    Pages 69-83
  4. Prognostic Factors in Classic Myeloproliferative Neoplasms

    • Francisco Cervantes, Juan-Carlos Hernández-Boluda
    Pages 85-96
  5. Therapy of Polycythemia Vera and Essential Thrombocythemia

    • Guido Finazzi, Tiziano Barbui
    Pages 97-115
  6. Hematopoietic Cell Transplantation for Myelofibrosis

    • Daniella M. B. Kerbauy, H. Joachim Deeg
    Pages 139-150
  7. JAK2 Inhibitors for Therapy of Myeloproliferative Neoplasms

    • Fabio P. S. Santos, Srdan Verstovsek
    Pages 151-167
  8. Back Matter

    Pages 223-228

About this book

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.

Editors and Affiliations

  • M.D. Anderson Cancer Center, Dept. Leukemia, University of Texas, Houston, USA

    Srdan Verstovsek

  • Dept. Internal Medicine, Div. Hematology, Mayo Clinic, Rochester, USA

    Ayalew Tefferi

Bibliographic Information

  • Book Title: Myeloproliferative Neoplasms

  • Book Subtitle: Biology and Therapy

  • Editors: Srdan Verstovsek, Ayalew Tefferi

  • Series Title: Contemporary Hematology

  • DOI: https://doi.org/10.1007/978-1-60761-266-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-60761-265-0Published: 21 October 2010

  • Softcover ISBN: 978-1-61779-711-8Published: 01 December 2012

  • eBook ISBN: 978-1-60761-266-7Published: 17 October 2010

  • Edition Number: 1

  • Number of Pages: X, 230

  • Topics: Hematology, Oncology, Angiology, Medical Biochemistry

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access