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Medicine - Internal Medicine | Cholesterol Transporters of the START Domain Protein Family in Health and… - START Proteins

Cholesterol Transporters of the START Domain Protein Family in Health and Disease

START Proteins - Structure and Function

Clark, Ph.D., Barbara J., Stocco, Douglas M. (Eds.)

2014, XIV, 190 p. 25 illus., 21 illus. in color.

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  • Focuses on Star function in non-steroidogenic tissues
  • Addresses the emerging possibilities for STARD4 and STARD5 in cholesterol homeostasis and dysregulation
  • Provides perspective to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process

Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer, and atherogenesis.

This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows, and endocrinology fellows on the research discovery process.

Content Level » Research

Keywords » cholesterol homeostasis - cholesterol transport - endocrinology - start transporters

Related subjects » Biomedical Sciences - Internal Medicine

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