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Mitochondrial Function in Lung Health and Disease

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  • © 2014

Overview

  • Comprehensive, state-of-the-art review
  • Written by experts in the field
  • Covers both research and clinical issues
  • Includes supplementary material: sn.pub/extras

Part of the book series: Respiratory Medicine (RM)

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Table of contents (9 chapters)

Keywords

About this book

Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.

Editors and Affiliations

  • Department of Pharmaology and Medicine, University of Illinois at Chicago, Chicago, USA

    Viswanathan Natarajan

  • Division of Allergy, Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, Ohio State University Wexner, Medical Center, Columbus, USA

    Narasimham L. Parinandi

Bibliographic Information

  • Book Title: Mitochondrial Function in Lung Health and Disease

  • Editors: Viswanathan Natarajan, Narasimham L. Parinandi

  • Series Title: Respiratory Medicine

  • DOI: https://doi.org/10.1007/978-1-4939-0829-5

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4939-0828-8Published: 26 July 2014

  • Softcover ISBN: 978-1-4939-4436-1Published: 17 September 2016

  • eBook ISBN: 978-1-4939-0829-5Published: 26 July 2014

  • Series ISSN: 2197-7372

  • Series E-ISSN: 2197-7380

  • Edition Number: 1

  • Number of Pages: XI, 222

  • Number of Illustrations: 10 b/w illustrations, 24 illustrations in colour

  • Topics: Pneumology/Respiratory System, Internal Medicine, Biomedicine general

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