Cardiac Adaptations

1. Front Matter

   Pages i-xvii

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2. DEVELOPMENTAL ASPECTS OF CARDIAC ADAPTATION

   1. Front Matter

      Pages 1-1

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   2. Comparative Aspects of Cardiac Adaptation

      • Bohuslav Ostadal

      Pages 3-18

   3. Molecular Mechanisms of Cardiac Development

      • Patricia Roche, Michael P. Czubryt, Jeffrey T. Wigle

      Pages 19-39

   4. Prenatal Adaptations to Overload

      • Zivorad Pesevski, David Sedmera

      Pages 41-57

   5. Hypoxia and Mechanical Factors Drive Coronary Vascular Development

      • Robert J. Tomanek

      Pages 59-77

   6. Cardiac Metabolic Adaptation During Postnatal Development

      • Jérôme Piquereau, Marta Novotova, Anne Garnier, Frédéric Joubert, Vladimir Veksler, Renée Ventura-Clapier

      Pages 79-98

   7. Ontogenetic Aspects of Cardiac Adaptation to Chronic Hypoxia

      • Bohuslav Ostadal, Ivana Ostadalova, Zuzana Charvatova, Frantisek Kolar

      Pages 99-110

   8. Heart and Arterial Aging

      • Paul D. Chantler, Edward G. Lakatta

      Pages 111-144

3. CARDIAC ADAPTATIONS TO OVERLOAD

   1. Front Matter

      Pages 145-145

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   2. Differences in Concentric Cardiac Hypertrophy and Eccentric Hypertrophy

      • Alison L. Müller, Naranjan S. Dhalla

      Pages 147-166

   3. Cardiac Adaptation to Volume Overload

      • Vojtech Melenovsky

      Pages 167-199

   4. Functional Adaptation During the Development of Cardiac Hypertrophy and Heart Failure in Females

      • Melissa R. Dent, Vijayan Elimban, Amrit Malik, Paramjit S. Tappia, Naranjan S. Dhalla

      Pages 201-212

   5. Impact of Gender and Exercise on Cardiac Adaptation to Pathological Situations: Sex Hormones, Exercise and Cardiac Adaptation

      • Feriel Azibani, Claude Delcayre, Jane-lise Samuel

      Pages 213-231

   6. Cardiopulmonary Adaptation to High Altitude

      • Jean-Paul Richalet

      Pages 233-249

   7. Cardiac Hypertrophy in Hypertension

      • Jaroslav Kuneš, Ivana Vaněčková, Michaela Kadlecová, Michal Behuliak, Zdenka Dobešová, Josef Zicha

      Pages 251-267

   8. Exercise Training and Adverse Cardiac Remodeling and Dysfunction in Mice

      • Dirk J. Duncker, Elza D. van Deel, Monique C. de Waard, Jolanda van der Velden

      Pages 269-287

   9. The Athlete’s Heart

      • Aaron L. Baggish

      Pages 289-302

4. MOLECULAR AND CELLULAR ASPECTS OF CARDIAC ADAPTATIONS

   1. Front Matter

      Pages 303-303

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   2. Role of β-Adrenoceptor/Adenylyl Cyclase System in Cardiac Hypertrophy

      • Adriana Adameova, Paramjit S. Tappia, Naranjan S. Dhalla

      Pages 305-324

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia.  Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.

• biochemical mechanisms
• cardiac development
• molecular biology
• myocardial
• physiology
• signal transduction
• Receptors

• Czech Republic, Institute of Physiology, Academy of Sciences of the, Prague, Czech Republic

  Bohuslav Ostadal

• St. Boniface General Hospital, Research Centre, Institute of Cardiovascular Sciences, Winnipeg, Canada

  Naranjan S. Dhalla

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