Overview
- Attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states
Part of the book series: Medical Intelligence Unit (MIUN)
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Table of contents(10 chapters)
About this book
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.
Authors and Affiliations
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Department of Internal Medicine and Physiology Life Sciences Institute, The University of Michigan Medical Center, Ann Arbor, USA
Alan R. Saltiel
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Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, USA
Jeffrey E. Pessin
Bibliographic Information
Book Title: Mechanisms of Insulin Action
Authors: Alan R. Saltiel, Jeffrey E. Pessin
Series Title: Medical Intelligence Unit
DOI: https://doi.org/10.1007/978-0-387-72204-7
Publisher: Springer New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag New York 2007
Hardcover ISBN: 978-0-387-72203-0
Softcover ISBN: 978-1-4419-2469-8
eBook ISBN: 978-0-387-72204-7
Edition Number: 1
Number of Pages: XI, 214
Topics: Endocrinology, Cell Biology, Diabetes, Cardiology