Skip to main content
SpringerLink
Log in

Metabolic Basis of Obesity

  • Book
  • © 2011

Overview

Editors:
  1. Rexford S. Ahima

    1. School of Medicine, Div. Endocrinology, Diabetes, &, University of Pennsylvania, Philadelphia, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Provides a unique framework for understanding the biological basis of obesity

  • Comprehensive, covering key scientific and clinical aspects

  • Developed by a team of expert authors

  • Discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, among other topics

  • Reviews current and future diagnostic and treatment strategies

  • Includes supplementary material: sn.pub/extras

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Principles of Human Energy Metabolism

    • Jose Galgani, Eric Ravussin
    Pages 1-23

  3. Intermediary Metabolism of Carbohydrate, Protein, and Fat

    • Keith Tornheim, Neil B. Ruderman
    Pages 25-51

  4. Adipose Tissue Development, Structure and Function

    • Jaswinder K. Sethi, Antonio J. Vidal-Puig
    Pages 53-68

  5. Adipokines in Health and Disease

    • Rexford S. Ahima, Marcus D. Goncalves
    Pages 69-88

  6. Neural Control of Feeding and Energy Homeostasis

    • Emilie Caron, Rexford S. Ahima
    Pages 89-107

  7. Gastrointestinal Hormones and Obesity

    • Yan Wang, Efi Kokkotou
    Pages 109-125

  8. Genes and Human Obesity

    • R. Arlen Price
    Pages 127-138

  9. Classical Hormones Linked to Obesity

    • Hyeong-Kyu Park, Rexford S. Ahima
    Pages 139-154

  10. Inflammation and Adipose Dysfunction

    • Rachana Shah, Muredach P. Reilly
    Pages 155-173

  11. Insulin Resistance in the Metabolic Syndrome

    • Sudha B. Biddinger, Brice Emanuelli
    Pages 175-198

  12. Pancreatic Islet β-Cell Failure in Obesity

    • Tomoaki Morioka, Rohit N. Kulkarni
    Pages 199-217

  13. Non-Alcoholic Fatty Liver Disease and the Metabolic Syndrome

    • Sonia M. Najjar
    Pages 219-227

  14. Sleep, Circadian Rhythms and Metabolism

    • Eleonore Maury, Kathryn Moynihan Ramsey, Joseph Bass
    Pages 229-255

  15. Obesity and Cardiac Dysfunction

    • Gary Sweeney, Sheldon E. Litwin, Evan Dale Abel
    Pages 257-292

  16. Atherogenic Lipid Metabolism in Obesity

    • Sue-Anne Toh, Michael Levin, Daniel J. Rader
    Pages 293-309

  17. Gut Microbes, Immunity, and Metabolism

    • Evelyn Hsu, Gary Wu
    Pages 311-330

  18. Impact of Obesity on Female Reproductive Health

    • Moshood O. Olatinwo, Djana Harp, Winston Thompson, Hyeong-Kyu Park, Roland Mathews
    Pages 331-341

  19. Lessons from HIV Lipodystrophy and Drug-Induced Metabolic Dysfunction

    • Steven Grinspoon
    Pages 343-358

  20. Principles of Obesity Therapy

    • Rexford S. Ahima
    Pages 359-379
Back to top

Keywords

About this book

The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.

Reviews

From the reviews:

“This book presents in-depth reviews on a wide variety of topics related to the metabolic basis of obesity. … The book is written for researchers, clinicians, students, and the public at large. … it is most appropriate for researchers and clinicians who focus on patients with metabolic disorders. … This is a great book on the metabolic basis of obesity. It is a fantastic place to start for researchers and clinicians who wish to obtain a deeper understanding of this timely and important area.” (Ronald N. Cohen, Doody’s Review Service, April, 2011)

Editors and Affiliations

  • School of Medicine, Div. Endocrinology, Diabetes, &, University of Pennsylvania, Philadelphia, USA

    Rexford S. Ahima

Bibliographic Information

  • Book Title: Metabolic Basis of Obesity

  • Editors: Rexford S. Ahima

  • DOI: https://doi.org/10.1007/978-1-4419-1607-5

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-4419-1606-8Published: 17 November 2010

  • Softcover ISBN: 978-1-4899-8202-5Published: 01 November 2014

  • eBook ISBN: 978-1-4419-1607-5Published: 16 November 2010

  • Edition Number: 1

  • Number of Pages: XIV, 391

  • Topics: Endocrinology, Gastroenterology, Neurosciences, Human Physiology

Publish with us

Policies and ethics

Back to top

Search

Navigation