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Calcium-Sensing Receptor provides an overview of various aspects of the calcium receptor's biochemistry, physiology and pathophysiology that is suitable both for those who have been working in the field of Ca2+0-sensing as well as those who are new to this discipline. Calcium-Sensing Receptor is the nineteenth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Contributors. Preface; N. Chattopadhyay, E.M. Brown. 1. An overview of extracellular calcium homeostasis and the roles of the CaR in the parathyroid and C-cells; A. Mithal, E.M. Brown. 2. Structure-function relationship of the extracellular calcium-sensing receptor; Mei Bai. 3. Calcium receptor-mediated signaling; K.D. Rodland. 4. Extracellular Ca2+- sensing receptor and kidney function; D. Riccardi, S.C. Hebert. 5. Calcium- sensing receptor in bone; T. Yamaguchi. 6. Functions in the calcium-sensing receptor in the gastrointestinal system; R.J. MacLeod. 7. The calcium-sensing receptor (CaR) and human disease; C.H. Kos, M.R. Pollak. 8. Compounds acting on the parathyroid calcium receptor as novel therapies for hyperparathyroidism or osteoporosis; E.F. Nemeth, J. Fox. 9. Alternative agonists and modulators: evidence that the calcium sensing receptor is a multi-modal sensor; S.J. Quinn, A.D. Conigrave. 10. Expression and functions of calcium-sensing receptor in the central nervous system; Chianping Ye, et al. 11. The role of the calcium receptor in calcium regulated keratinocyte differentiation; Chia-Ling Tu, et al. Calcium sensing receptor and neoplastic transformation; E. Kállay, et al.