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Prolactin

  • Book
  • © 2001

Overview

Editors:
  1. Nelson D. Horseman

    1. University of Cincinnati, USA

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Part of the book series: Endocrine Updates (ENDO, volume 12)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-vii
    Download chapter PDF

  2. Hypothalamic Control of Prolactin Synthesis and Secretion

    • Nira Ben-Jonathan
    Pages 1-24

  3. Role of Prolactin in Developmental Differentiation of Hypothalamic Dopaminergic Neurons

    • Carol J. Phelps, David L. Hurley
    Pages 25-43

  4. Mechanisms of Dopamine Action on the Lactotroph

    • Karen A. Gregerson
    Pages 45-61

  5. Regulation of Lactotrophs and Prolactin Secretion in Non-mammalian Vertebrates

    • Tom E. Porter, Mohamed E. El Halawani
    Pages 63-79

  6. Prolactinomas

    • Mark E. Molitch
    Pages 81-99

  7. The Psychosomatic Interface: Hyperprolactinemia

    • Luis G. Sobrinho
    Pages 101-117

  8. Genetics of Prolactinomas

    • Toni R. Prezant
    Pages 119-137

  9. Rodent Prolactin Family and Pregnancy

    • Michael J. Soares, Daniel I. H. Linzer
    Pages 139-167

  10. Human Uteroplacental Lactogens: Physiology and Molecular Biology

    • Stuart Handwerger, Anoop Brar
    Pages 169-187

  11. Structure-Function Relationships in Prolactin

    • Mary Y. Lorenson, Ameae M. Walker
    Pages 189-217

  12. Mammary Gland Development

    • Christopher J. Ormandy, Nelson D. Horseman, Matthew J. Naylor, Jessica Harris, Fiona Robertson, Nadine Binart et al.
    Pages 219-232

  13. Actions of Prolactin in the Prostate Gland

    • J. Kindblom, K. Dillner, J. Törnell, H. Wennbo
    Pages 233-245

  14. Prolactin Regulation of Cell Proliferation and Apoptosis

    • Arthur R. Buckley
    Pages 247-264

  15. Mechanisms of Luteal Cell Regulation by Prolactin

    • Michael Risk, Geula Gibori
    Pages 265-295

  16. Regulation of Pancreatic Islets by Prolactin, Growth Hormone and Placental Lactogen

    • Robert L. Sorenson, T. Clark Brelje
    Pages 297-316

  17. In Vitro Effects of Prolactin on the Lympho-Hemopoietic System

    • Elizabeth L. Hooghe-Peters, Zeynep Dogusan, Robert Hooghe
    Pages 317-339

  18. Prolactin Receptors

    • Marc Edery, Nadine Binart, Brigitte Bouchard, Vincent Goffin, Paul A. Kelly
    Pages 341-353

  19. Prolactin Receptor Signal Transduction

    • Charles V. Clevenger, Michael A. Rycyzyn, Farhat Syed, J. Bradford Kline
    Pages 355-379

  20. Transcription Factors, Cofactors and Target Genes Mediating Prolactin Signals

    • Carrie S. Shemanko, Bernd Groner
    Pages 381-404
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Keywords

About this book

It is an authentic privilege to have the opportunity to assemble and edit a new volume on "Prolactin," the first in several decades to be devoted to this fascinating hormone in all its aspects. The obvious clinical rationale for understanding prolactin (PRL) is the frequent occurrence of prolactinomas, the most common type of pituitary tumor. Fortunately, medical management of prolactinomas can be based on our under­ standing of the physiology of hypothalamic control of the lactotroph. Armed with this knowledge, therapies for proiactinomas are highly successful and well tolerated. Be­ cause of the historical and practical importance of knowledge regarding the hypothala­ mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation. Chapters focusing on prolactinomas and related clinical issues follow these. PRL is the primary hormone that is responsible for "parental care" in many verte­ brate species. This reproductive strategy is not unique to mammals, but it has devel­ oped through evolution to be the central distinguishing feature of the mammalian life cycle. Among the mammals, mice have become the most effective research species in recent years. This can be traced to the development of a wide range of methods for manipulating mouse genetics, and thereby influencing development, physiology and behavior. Mice also provide a profound illustration of the physiological challenges faced in maternity. Female mice undergo a post-partum estrous, and often are both pregnant and lactating simultaneously.

Editors and Affiliations

  • University of Cincinnati, USA

    Nelson D. Horseman

Bibliographic Information

  • Book Title: Prolactin

  • Editors: Nelson D. Horseman

  • Series Title: Endocrine Updates

  • DOI: https://doi.org/10.1007/978-1-4615-1683-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2001

  • Hardcover ISBN: 978-0-7923-7290-5Published: 31 January 2001

  • Softcover ISBN: 978-1-4613-5676-9Published: 24 October 2012

  • eBook ISBN: 978-1-4615-1683-5Published: 06 December 2012

  • Series ISSN: 1566-0729

  • Edition Number: 1

  • Number of Pages: VII, 412

  • Topics: Diabetes, Cancer Research, Biochemistry, general, Internal Medicine

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