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  • © 2014

Epidemiology of Human Congenital Malformations

Authors:

  • Only book available exclusively covering the epidemiology of human congenital malformations and possible risk factors

  • Based on the analysis of data from the Swedish National Health registers for the period 1998-2010, corresponding to some 1.3 million births

  • Authored by Professor Emeritus Bengt Källén, ?an internationally recognised expert in the field of birth defect epidemiology ?

  • Includes supplementary material: sn.pub/extras

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-ix
  2. Statistical Considerations

    • Bengt Källén
    Pages 13-16
  3. Epidemiological Methods

    • Bengt Källén
    Pages 17-19
  4. Neural Tube Defects

    • Bengt Källén
    Pages 21-25
  5. Microcephaly

    • Bengt Källén
    Pages 27-31
  6. Hydrocephaly

    • Bengt Källén
    Pages 33-36
  7. Severe Eye Malformations

    • Bengt Källén
    Pages 41-43
  8. Severe Ear Malformations

    • Bengt Källén
    Pages 45-48
  9. Cardiovascular Defects

    • Bengt Källén
    Pages 49-72
  10. Orofacial Clefts

    • Bengt Källén
    Pages 73-77
  11. Atresia or Stenosis of the Alimentary Tract

    • Bengt Källén
    Pages 79-83
  12. Pyloric Stenosis

    • Bengt Källén
    Pages 85-88
  13. Malrotation of the Gut

    • Bengt Källén
    Pages 89-91
  14. Megacolon

    • Bengt Källén
    Pages 93-94
  15. Hypospadias

    • Bengt Källén
    Pages 95-98
  16. Epispadias, Cloacal and Bladder Exstrophy

    • Bengt Källén
    Pages 99-102

About this book

Authored by Bengt Källén, professor emeritus in embryology at Lund University in Sweden.

​​The subject of this book is to describe the occurrence of congenital malformations among children born and what risk factors exist. Population data are presented for a number of malformations, ascertained with the use of data from the Swedish national health registers for the period 1998-2010 corresponding to some 1.3 million births, together with prospectively collected information on a group of exposures of possible interest. The structure of the analysis is such that it excludes studies of, for instance, nutrition, alcohol or street drug use and many other lifestyle factors where prospective information or independent register information is difficult or impossible to obtain.

Epidemiology of Human Congenital Malformations culminates with a discussion on how the presence of malformations can be explained and various possibilities for the prevention of birth defects. Moreover, it will include a series of instructions on how to read epidemiological literature in this field making it an essential resource both for those currently working in the field of reproductive epidemiology or those intending to enter it. It will additionally be useful for doctors working with malformations, either as obstetricians, neonatologists or pediatricians.

Reviews

From the book reviews:

“A concise text based on a register performed by the Swedish National Board of Health and Welfare. In addition to the description of a long list of birth defects with bibliography, the last chapter contains a discussion on the explanation and prevention of these defects. For obstetricians, geneticists and neonatologists.” (Pediatric Endocrinology Reviews (PER), Vol. 12 (1), September, 2014)

“Dr. Bengt Kallen relates his 50-plus years of experience in reproductive epidemiology in this collection that describes the epidemiology of human congenital malformations. … This is a well-organized compilation of decades worth of research, and is a very useful resource for clinicians or researchers in the field of birth defects epidemiology.” (Kelli K. Ryckman, Doody’s Book Reviews, February, 2014)

Authors and Affiliations

  • Tornblad Institute, Lund, Sweden

    Bengt Källén

About the author

Bengt Källén is professor emeritus of embryology at Lund University in Sweden. He has been working in birth defect epidemiology since the 1960s and was one of the founders of the Swedish Register of Congenital Malformations, one of the first registers started after the thalidomide tragedy around 1960. He worked for many years in the International Clearinghouse for Birth Defects Monitoring Systems and has published numerous scientific articles on congenital malformations, most notably on the effect of maternal drug use and in vitro fertilization.

Bibliographic Information

  • Book Title: Epidemiology of Human Congenital Malformations

  • Authors: Bengt Källén

  • DOI: https://doi.org/10.1007/978-3-319-01472-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2014

  • Hardcover ISBN: 978-3-319-01471-5Published: 11 October 2013

  • Softcover ISBN: 978-3-319-34898-8Published: 23 August 2016

  • eBook ISBN: 978-3-319-01472-2Published: 04 October 2013

  • Edition Number: 1

  • Number of Pages: IX, 170

  • Number of Illustrations: 32 illustrations in colour

  • Topics: Obstetrics/Perinatology/Midwifery, Maternal and Child Health, Reproductive Medicine, Epidemiology, Pediatrics

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access