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Oocyte Biology in Fertility Preservation

  • Book
  • © 2013

Overview

  • Addresses oocyte preservation, one of the most controversial topics in reproductive biology
  • Focuses on many different aspects of ovarian biology
  • Explores the wisdom of the experimental practice of oocyte preservation while considering new reproductive technologies
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 761)

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Table of contents (7 chapters)

Keywords

About this book

​Fertility preservation has become one of the most important and fast growing fields of reproductive medicine.  Although there are several strategies for fertility preservation in female, most of them are still considered experimental.  It is important to perfect the existing technologies, but also developing new strategies should be actively sought.  The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles.  One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms.  To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level.  Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation.  The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics.​ 

Editors and Affiliations

  • University of Kansas Medical Center, Kansas City, USA

    S. Samuel Kim

About the editor

S. Samuel Kim is on the editorial board of the Journal of Assisted Reproduction and Genetics, an official publication of the American Society for Reproductive Medicine. He works closely with the journal's Editor-in-Chief, David Albertini, at the University of Kansas Medical Center, with which they are both affiliated.

Bibliographic Information

  • Book Title: Oocyte Biology in Fertility Preservation

  • Editors: S. Samuel Kim

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4614-8214-7

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2013

  • Hardcover ISBN: 978-1-4614-8213-0Published: 06 October 2013

  • Softcover ISBN: 978-1-4939-4574-0Published: 23 August 2016

  • eBook ISBN: 978-1-4614-8214-7Published: 05 October 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 97

  • Number of Illustrations: 3 b/w illustrations, 9 illustrations in colour

  • Topics: Reproductive Medicine, Cell Biology, Molecular Medicine

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