Longevity & Healthspan is an open access, peer-reviewed, interdisciplinary journal that publishes articles on all aspects of aging biology in the context of healthy aging or age-related disease. More specifically, the journal emphasizes advancing understanding of how age-related changes in structure and function become risk factors for or accompany age-related diseases or conditions, and the biology underlying healthy aging and longevity.
Experimental approaches include biochemistry, molecular genetics, genome-wide association studies, cell biology, and interventional studies.
The journal welcomes articles in particular in the following areas:
- Development of criteria to define successful aging in humans or model organisms
- Development of genetically tractable animal models assessing healthspan or age-related conditions
- Interdisciplinary studies involving both aging and age-related disease specialists
- Studies of candidate genes or pathways that correlate with age-related conditions
- Studies on the biology of healthy aging and longevity
- Translational studies validating interventions to increase healthspan and/or longevity
Epidemiological studies and studies of interventions targeting age-related conditions with concurrent study of other age-associated end points will also be given consideration.
Aging represents the most important risk factor for chronic disease, frailty, and loss of independence, making an understanding of the mechanisms by which aging curtails healthspan and leads to disease highly desirable from both a social and economic standpoint. Longevity & Healthspan bridges the gap between research on the basic biology of aging and clinical dysfunction associated with the aging process.