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Medicine - Family & Geriatric Medicine | Oxidative Stress and Aging: - From Chemistry to Human Dietary Supplements

Oxidative Stress and Aging:

From Chemistry to Human Dietary Supplements

Series: Aging Medicine

Hoshi, Toshinori, Pignolo, Robert J., Heinemann, Stefan H. (Eds.)

2013, Approx. 400 p. 50 illus..

A product of Humana Press
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  • About this book

  • Offers thorough coverage of pro- and anti-oxidant components, with discussion of their human implications
  • Examines oxidative stress and aging in ascending stages of complexity, from molecules to organisms
  • Includes a chapter on possible lifespan extension strategies

Oxidative stress and aging is a multi-dimensional/factorial subject matter encompassing different degrees of organism complexity (from single-cell animals to humans), different molecules (DNA, RNAs, proteins and lipids), different cellular components (mitochondria, cytoplasm and plasma membrane), different tissues and organs, and different human subpopulations including those with different "lifestyles." This book roughly follows this complexity hierarchy, from molecules to organisms; and within each section, pro- and anti-oxidant components will be presented and human implications will be discussed. Some overlap in coverage of topics is anticipated and this is deemed both necessary and preferable for the existing literature is often controversial. The book concludes with a chapter focusing on possible lifespan extension strategies based on our understanding of oxidative stress protection. A short preface in each of the major sections will be included to summarize the section and briefly mention other topics not specifically covered by the chapters within. The following chapter titles are tentative and will be adjusted according the contributors’ preferences.

Content Level » Research

Related subjects » Biochemistry & Biophysics - Family & Geriatric Medicine - Immunology - Internal Medicine - Medicine - Molecular Medicine

Table of contents 

Section I

Introduction

    1. Oxidation, Aging and lifespan: an overview and a brief assessment of the oxidative damage theory of aging.
      1. Arlan Richardson, Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 richardsona@uthscsa.edu

    2. Experimental measurements and statistical analysis of aging and lifespan
      1. David Allison, University of Alabama Birmingham, Birmingham, AL. dallison@uab.edu

    3. Oxidative chemistry and markers of damaged molecules
      1. Harry Ischiropoulos, University of Pennsylvania, Philadelphia, PA


        Section II Oxidative Stress Targets and Aging

    4. DNA damage
      1. Ryszard Olinksy, Department of Clinical Biochemistry, Nicolaus Copernicus University, Poland. ryszardo@cm.umk.pl.

    5. Regulatory RNAs as a modulator of aging and lifespan.
      1. Frank Slack, Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT. Frank.slack@yale.edu.

    6. Amino-acid/protein oxidation and aging I
      1. Wulf Dröge, Immunotec Ressearch, Quebec, Canada. w.droege@immunotec.com.
      2. Or
      3. Thomas Squier, Pacific Northwest National Laboratory, Richland, WA. Thomas.Squier@pnl.gov.

    7. Selenoprotein and aging
      1. Helmut Sies, Dusseldorf, Germany. sies@uni-duesseldorf.de

    8. Oxidation of lipids in aging
      1. Rochelle Buffenstein, Department of Biology, City College of the City University of New York, NY. rbuffen@sci.ccny.cuny.edu.

    9. AGE in aging
      1. Sho-ichi Yamagishi, Department of Medicine, Kurume University, Japan. shoichi@med.kurume-u.ac.jp.


      Section III OxidativeDamage to Subcellular Compartments

    10. Oxidative damage to mitochondria and aging
      1. Martin Brand, MRC Dunn Human Nutrition MRC, U.K. martin.brand-web@mrc-dunn.cam.ac.uk
      2. Or
      3. Heinz-Dieter Osiewacz, Johann Wolfgang Goethe University Franfurt, Germany. osiewacz@em.uni-frankfurt.de

    11. Oxidative stress and cellular energy failure
      1. Pidder Jansen-Düerr, Insbruck, Austria. pidder.jansen-duerr@oeaw.ac.at

    12. P66shc regulation in aging and lifespan
      1. Pier Giuseppe Pelicci, Milan, Italy. piergiuseppe.pelicci@ifom-ieo-campus.it

      Section IV Oxidative Damage to Organs and Aging

    13. Brain: oxidative stress and aging brain
      1. Christian Behl, Max Planck Institute of Psychiatry, Munich, Germany. chris@mpipsykl.mpg.de

    14. Cardiovascular system
      1. Norbert Latruffe, Department of molecular and cell biology, University of Burgndy, France. latruffe@u-bourgogne.fr.

    15. Musculoskeletal system and aging
      1. Li Li Ji, The Biodynamics Laboratory, University of Wisconsin-Madison, Madison, WI 53706. ji@education.wisc.edu
      2. (We may ask him to focus on the skeletal muscle system instead of the overall "physical activity" at a higher level – see below).

        Section V Interplay with Other Modulatory Factors of Aging

    16. Caloric restriction and oxidative stress I
      1. R. S. Sohal, Department of Molecular Pharmacology and Toxicology, University of Southern California, Los Angeles, CA 90089.

    17. Caloric restriction and oxidative stress II
      1. Michael Ristow, Department of Human Nutrition, Institute of Nutrition, University of Jena, D-07743 Jena, Germany.

    18. Physical activity, oxidative stress and aging I
      1. Li Li Ji, The Biodynamics Laboratory, University of Wisconsin-Madison, Madison, WI 53706. ji@education.wisc.edu

    19. Physical activity, oxidative stress and aging II
      1. Zsolt Radak, Institute of Sport Science, Faculty of Physical Education and Sport Science, Semmelweis University, Budapest, Hungary. radak@mail.hupe.hu. Alternatively, Sataro Goro, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.

        Section VI Nutritional Approaches to Minimize Oxidative Stress and Aging

    20. Nutritional supplements and oxidative stress and aging
      1. James Joseph, USDA & Tufts University, Boston MA. Jim.joseph@ars.usda.gov

    21. Garlic, oxidative stress and aging
      1. Carmia Borek, Department of Public Health and Family Medicine, Tufts University, Boston, MA. carmia.borek@tufts.edu

    22. Resveratrol and other plant polyphenols
      1. To be determined.

    23. Cognitive decline with aging and oxidative stress
      1. Norton Milgram, Department of Pharmacology, University of Toronto, Toronto, Canada. milgram@utsc.utoronto.ca

        Section VII Healthy Aging Strategy Based on Oxidative Stress Protection

    24. Healthy aging strategies
      1. Bruce Ames, University of California, Berkeley, CA. bnames@berkeley.edu.

And/or

Khalid Rahman, School of Biomolecular Sciences, Liverpool John Moores University, UK. k.rahman@livjm.ac.uk.

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