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Neuroimmunology of the Skin

Basic Science to Clinical Practice

  • Up-to-date, comprehensive and concise book on the important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin

  • Written by leading experts in the world in these areas

  • Highly structured with reader-friendly format (core messages, etc.)

  • Of interest to both researchers and clinicians of various disciplines (dermatologists, neurologists, psychiatrists, etc.)

  • Includes supplementary material: sn.pub/extras

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xi
  2. Basic Neuroimmunology of the Skin

    1. Neuroanatomy of the Skin

      • D. Metze
      Pages 3-12
    2. Neuroreceptors and Mediators

      • S. Ständer, T. A. Luger
      Pages 13-22
    3. Autonomic Effects on the Skin

      • F. Birklein, T. Schlereth
      Pages 23-32
    4. Immune Circuits of the Skin

      • E. Weinstein, R. D. Granstein
      Pages 33-44
    5. Modulation of Immune Cells by Products of Nerves

      • A. M. Bender, R. D. Granstein
      Pages 45-53
    6. Regulation of Immune Cells by POMC Peptides

      • T. A. Luger, T. Brzoska, K. Loser, M. Böhm
      Pages 55-63
    7. Neuroinflammation and Toll-Like Receptors in the Skin

      • B. Rothschild, Y. Lu, H. Chen, P. I. Song, C. A. Armstrong, J. C. Ansel
      Pages 89-102
  3. Neurobiology of Skin Appendages

    1. Neurobiology of Hair

      • D. J. Tobin, E. M. J. Peters
      Pages 139-157
    2. Neurobiology of Sebaceous Glands

      • M. Böhm, T. A. Luger
      Pages 159-166
    3. Neurobiology of Skin Appendages: Eccrine, Apocrine, and Apoeccrine Sweat Glands

      • K. Wilke, A. Martin, L. Terstegen, S. S. Biel
      Pages 167-175
  4. The Nervous System and the Pathophysiology of Skin Disorders

    1. Neurophysiology of Itch

      • G. Yosipovitch, Y. Ishiuji
      Pages 179-186
    2. Neuroimmunologic Cascades in the Pathogenesis of Psoriasis and Psoriatic Arthritis

      • S. P. Raychaudhuri, S. K. Raychaudhuri
      Pages 187-196
    3. Neuroimmunology of Atopic Dermatitis

      • A. Steinhoff, M. Steinhoff
      Pages 197-207
    4. Stress and Urticaria

      • M. A. Gupta
      Pages 209-217

About this book

Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.

Reviews

From the reviews:

"Granstein and Luger boldly went where no one has gone before. … they have successfully compiled a book which cuts across scientific disciplines, ranging from dermatology, immunology, neurobiology and psychology. … it is a useful tool to comprehend how the psychological state – such as stress perception – triggers or aggravates skin diseases. … The book gives valuable inspiration for both, basic scientists and clinicians, and future cross-cutting research endeavours as well as their clinical translation can be envisioned to arise from reading this book." (Petra Arck, Journal der Deutschen Dermatologischen Gesellschaft, Vol. 7 (11), November, 2009)

Editors and Affiliations

  • Weill Cornell Medical College Department of Dermatology, Cornell University, New York, USA

    Richard D. Granstein

  • Medizinische Einrichtungen Klinik und Poliklinik für, Universitätsklinikum Münster, Münster, Germany

    Thomas A. Luger

Bibliographic Information

  • Book Title: Neuroimmunology of the Skin

  • Book Subtitle: Basic Science to Clinical Practice

  • Editors: Richard D. Granstein, Thomas A. Luger

  • DOI: https://doi.org/10.1007/978-3-540-35989-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2009

  • Hardcover ISBN: 978-3-540-35986-9Published: 14 November 2008

  • Softcover ISBN: 978-3-642-07151-5Published: 14 October 2010

  • eBook ISBN: 978-3-540-35989-0Published: 08 February 2009

  • Edition Number: 1

  • Number of Pages: XI, 251

  • Topics: Dermatology, Psychiatry, Neurology, Immunology, Neurosciences

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access