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The Etiology of Atopic Dermatitis

  • Book
  • © 2015

Overview

Authors:
  1. Herbert B. Allen

    1. Drexel University Department of Dermatology, Philadelphia, USA

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  • Highly illustrated diagnostic review of atopic dermatitis

  • Concise approach with the emphasis on immediate application of knowledge

  • Presents key concepts in an easy understandable format

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Clinical Presentations

    • Herbert B. Allen
    Pages 1-14

  3. Microbiology

    • Herbert B. Allen
    Pages 15-24

  4. Pathology

    • Herbert B. Allen
    Pages 25-34

  5. Immunology

    • Herbert B. Allen
    Pages 35-42

  6. Genetics

    • Herbert B. Allen
    Pages 43-49

  7. Physiology

    • Herbert B. Allen
    Pages 51-56

  8. Treatment

    • Herbert B. Allen
    Pages 57-68

  9. Diseases in Which Eczema Is a Secondary Component (Meyerson’s Nevus and Doucas Kapetanakis Pigmented Purpuric Dermatosis)

    • Herbert B. Allen
    Pages 69-74

  10. Diseases with Occluded Sweat Ducts other than Eczema (Tinea Pedis, Axillary Granular Parakeratosis, and Seborrheic Dermatitis)

    • Herbert B. Allen
    Pages 75-95

  11. The Story of Eczema in Pictures

    • Herbert B. Allen
    Pages 97-106

  12. Epilogue: A Comparison of Psoriasis and Eczema: Both Caused by Bacteria, but Neither an Infection

    • Herbert B. Allen
    Pages 107-112

  13. Back Matter

    Pages 113-117
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Keywords

About this book

This book will present completely new, unique findings in eczema: sweat ducts that become occluded with staphylococcal biofilms trigger the innate immune system with TLR2 receptor activity and this leads to production of the “itching” and inflammation in this disease. Dermatologists and pediatricians treat eczema exceedingly well and this is ordinarily accomplished with corticosteroid containing topicals. However, after treatment, it is intriguing that aggressive moisturization and cautious bathing will in most instances prevent future flares of the disease, even though it is precipitated by bacteria and their biofilms. Diseases where eczema has been found with a completely unrelated disorder have shown occluded sweat ducts on histopathologic examination. These include Meyerson’s nevus which has a nevus and eczema in the same biopsy and Doucas Kapetanakis-type of pigmented purpuric dermatosis that shows occluded sweat ducts along with the capillaritis.

Reviews

“The purpose is to present the biofilm bacterial occlusion theory as the inciting inflammatory immune event leading to eczema. The audience is all primary physicians and dermatologists.” (Patricia Wong, Doody’s Book Reviews, November, 2015)

Authors and Affiliations

  • Drexel University Department of Dermatology, Philadelphia, USA

    Herbert B. Allen

About the author

Dr. Allen is a graduate of Johns Hopkins University School of Medicine. He has served on the boards of the American Society of Dermatology and the American College of Physicians and has published over 40 scientific articles in the fields of dermatology and dermatopathology. For the past ten years, he has been the Professor and Chair of the Department of Dermatology of Drexel University College of Medicine. Dr. Herbert B. Allen’s specialties include dermatology and dermatopathology, skin pathology and fungal infections and is board-certified with the American Board of Dermatology and the American Board of Pathology.

Bibliographic Information

  • Book Title: The Etiology of Atopic Dermatitis

  • Authors: Herbert B. Allen

  • DOI: https://doi.org/10.1007/978-1-4471-6545-3

  • Publisher: Springer London

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag London 2015

  • Hardcover ISBN: 978-1-4471-6544-6Published: 12 January 2015

  • Softcover ISBN: 978-1-4471-7255-0Published: 24 September 2016

  • eBook ISBN: 978-1-4471-6545-3Published: 29 October 2014

  • Edition Number: 1

  • Number of Pages: XVIII, 117

  • Number of Illustrations: 3 b/w illustrations, 108 illustrations in colour

  • Topics: Dermatology, Allergology

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