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The yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Multiple Organ Failure.- From Celsus to Galen to Bone: The Illnesses, Syndromes, and Diseases of Acute Inflammation.- Towards Understanding Pathophysiology in Critical Care: the Human Body as a Complex System.- Pediatric Sepsis and Multiple Organ Failure at the Millenium: A US Perspective.- Ventilator-Associated Systemic Inflammation.- Affecting Clinical Outcomes in Acute Respiratory Distress Syndrome with Enteral Nutrition.- Reducing Surgical Mortality and Complications.- New Developments in Sepsis.- Toll-like Receptors: Imphcation in Human Disease.- Poly (ADP-ribose) synthetase as a Novel Therapeutic Target for Circulatory Shock.- Inhibition of p38 Mitogen Activated Protein Kinase: A Novel Strategy in Sepsis?.- Acute Adrenal Insufficiency in Critically Ill Patients: the Waterhouse-Friderichsen Syndrome Revisited.- Coagulation Abnormalities.- Natural Anticoagulants in Disseminated Intravascular Coagulation and Sepsis.- Changes of the Hemostatic Network in the Critically Ill.- Infectious Problems.- Education as a Primary Tool for Prevention of Catheter-related Infections.- Antibiotic Resistance in the Intensive Care Unit.- Fungal Infection in Critically Ill Patients.- The Heart.- The ?3-Adrenoceptor and its Regulation in Cardiac Tissue.- Quantifying Myocardial Ejection Asynchrony: Effective Stroke Volume Analysis.- Determination of Afterload: A Promising Challenge for Echocardiography?.- From the Heart to the Cell.- Regional Differences in Vascular Reactivity in Sepsis and Endotoxemia.- Initial Clinical Experience with OPS Imaging for Observation of the Human Microcirculation.- Usefulness of Gastric Tonometry in Critically Ill Patients.- Monitoring Tissue Gas Tensions in Critical Illness.- Cell Function.- Lactate, Lactate/Pyruvate Ratio, Low Tissue Perfusion and Outcome.- Mitochondrial Antioxidant Activity and Disease Processes.- Reactive Nitrogen and Oxygen Species: Role and Evidence of their Production in Humans.- A Possible Role for Iron Ions in Organ Injury.- Blood Transfusions.- Optimizing Red Blood Cell Transfusion Practice.- Augmented Acute Normovolemic Hemodilution.- Polytrauma.- Permissive Hypotension during Primary Resuscitation from Trauma and Shock.- Hypertonic Resuscitation for Traumatic Brain Injury?.- Neurologic Crisis.- Severe Head Injury in Patients with Multiple Trauma.- Humoral and Neurological Mechanisms of Organ System Dysfunction in Patients with Central Nervous System Disease.- Cerebral Function in Coma, Vegetative State, Minimally Conscious State, Locked-in Syndrome, and Brain Death.- Multimodality Evoked Potentials in the Confirmation of Brain Death.- Acute Respiratory Failure.- Measurement and Interpretation of Lung Mechanics in Patients with Acute Respiratory Failure.- Lung Recruitment and Stabilization in ARDS.- Proportional Pressure Support in Acute Lung Injury.- The Role of Helium in the Treatment of Acute Respiratory Failure.- Intra-tracheal Aerosol Delivery in Intubated Patients.- Airway Pressure Release Ventilation: Time to Change the Concept?.- Weaning from Mechanical Ventilation and Non-Invasive Ventilation.- Weaning from Mechanical Ventilation (Part 1): Evidence Supports the Use of Protocols.- Weaning from Mechanical Ventilation (Part 2): Strategies for Implementing Protocols.- Non-Invasive Ventilation and Weaning from Mechanical Ventilation.- Non-Invasive Ventilation in Acute Hypoxemic Respiratory Failure.- Non-Invasive Mechanical Ventilation in Chronic Obstructive Pulmonary Disease.- Intra-abdominal Pressure.- Intra-abdominal Pressure in the Intensive Care Unit: Clinical Tool or Toy?.- Measuring Intra-abdominal Pressure in Intensive Care Setting.- Liver, Pancreas and Kidney.- The Splanchnic Circulation in Cirrhosis and Portal Hypertension.- Indocyanine Green for the Assessment of Liver Function in Critically Ill Patients.- Liver Support Systems.- Pancreatic Dysfunction in Critical Illness.- Acute Dialysis Quality Initiative.- ICU Organization.- Optimal Interhospital Transport Systems for the Critically Ill.- Outreach: A Hospital-wide Approach to Critical Illness.- Randomized Clinical Trials in Pediatric Critical Care.- Clinical Information Systems in the ICU.- Creating and Maintaining Safe Systems of ICU Care.- Ethical Questions for the New Millennium.