New Prospect of Vascular Medicine and Biology with Multidiscipline Approach
Tanishita, Kazuo, Yamamoto, Kimiko (Eds.)
2015, Approx. 420 p. 100 illus., 50 illus. in color.
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Examines the interdisciplinary field of vascular engineering from understanding the functionality of the circulatory system through to the implications for innovative medical treatments
Covers cutting edge research in molecular biology, biomedical engineering, and biophysics
Step-by-step explanations of methodology and the related background to educate medical professionals, researchers, engineers and graduate students
Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Understanding the dynamics of the circulatory system, and recognizing the impact of related disease conditions - atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction – has generated focus on developing the expertise to both maintain and treat the vascular system. This book reviews the fundamental biology and mechanics of the vasculature, and advances to examine how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. As a comprehensive text in this burgeoning area, Vascular Engineering, serves as a valuable resource to clinicians, as well as academics and professionals working in biophysics, biomedical engineering, nano- and micro-rheology. Graduate students in these subject areas will also find the text insightful.
Chapter 1 Introduction: The concept of vascular engineering and its biomechanical and clinical implications Chapter 2 Fundamentals of vascular bio-fluid and solid mechanics Chapter 3 Fundamentals of physiology and biology of vascular system Chapter 4 Hemodynamics in physio-and pathological vessels Blood flow in the physiological vessels and the role of blood flow for the localized formation of arterial disease such as atherosclerosis and aneurysm Chapter 5 Hemodynamics of micro-circulatory systems Chapter 6 Cellular biomechanics of vessel wall Chapter 7 Mechanotransduction of endothelial cells Chapter 8 Mechanobiology of endothelial cells related to the formation of arterial disease Chapter 9 Vascular engineering of blood coagulationDynamics of platelet aggregation and adhesion in the arterial vessels and its medical implications Chapter 10 Vascular engineering of endovascular treatment Chapter 11 Vascular engineering of circulatory assist devices Chapter 12 Innovation of vascular engineering by mechano-medicine Chapter 13 Integrated vascular engineering: Vascularization of reconstructed tissue Chapter 14 Future prospects of vascular engineering