Assessment of Preclinical Organ Damage in Hypertension

1. Front Matter

   Pages i-viii

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2. Heart

   1. Front Matter

      Pages 1-1

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   2. Evaluation of Cardiac Damage in Hypertension: Electrocardiography

      • Anders M. Greve, Peter M. Okin, Michael Hecht Olsen, Kristian Wachtell

      Pages 3-12

   3. Evaluation of Cardiac Damage in Hypertension: Echocardiography

      • Enrico Agabiti Rosei, Maria Lorenza Muiesan

      Pages 13-24

   4. Modern Diagnostic Approach for the Assessment of Cardiac Damage in Hypertension: 3D, CT and MRI

      • Athanasios J. Manolis, Eftichia Chamodraka, Ioanna Zacharopoulou

      Pages 25-37

3. Large Arteries

   1. Front Matter

      Pages 39-39

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   2. Ultrasound: Carotid Intima-Media Thickness and Plaque (2D–3D)

      • Enrico Agabiti Rosei, Massimo Salvetti, Maria Lorenza Muiesan

      Pages 41-50

   3. Echocardiographic Assessment of the Aorta and Coronary Arteries in Hypertensive Patients

      • Costas P. Tsioufis

      Pages 51-62

   4. Pulse Wave Velocity and Central Blood Pressure

      • Stéphane Laurent, Pierre Boutouyrie

      Pages 63-73

   5. Ankle-Brachial Index (ABI)

      • Denis L. Clement

      Pages 75-79

   6. Atherosclerosis and General Principles of Arterial Imaging

      • Isabel Gonçalves, Nuno V. Dias, Peter M. Nilsson

      Pages 81-95

   7. Imaging and Ageing of the Aorta and Large Arteries in the Lower Extremity

      • Nuno V. Dias, Isabel Gonçalves, Peter M. Nilsson

      Pages 97-114

4. Small Arteries

   1. Front Matter

      Pages 115-115

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   2. Micromyography

      • Enrico Agabiti Rosei, Damiano Rizzoni

      Pages 117-126

   3. Damage of Retinal Arterioles in Hypertension

      • Christian Ott, Roland E. Schmieder

      Pages 127-142

   4. Capillaroscopy

      • Enrico Agabiti Rosei, Carolina De Ciuceis, Damiano Rizzoni

      Pages 143-149

   5. Other Techniques for the Assessment of Small Artery Damage in Hypertension

      • Damiano Rizzoni, Claudia Agabiti Rosei

      Pages 151-156

5. Kidney

   1. Front Matter

      Pages 157-157

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   2. Proteinuria-Microalbuminuria in Renal Damage

      • Josep Redon, Gernot Pichler, Fernando Martinez

      Pages 159-164

   3. Glomerular Filtration Rate in Renal Damage

      • Josep Redon, Gernot Pichler, Fernando Martinez

      Pages 165-170

This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage in the general and the hypertensive population. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.

• Atherosclerosis
• Cardiovascular/renal structural changes
• Hypertensive population
• Left ventricular hypertrophy
• Preclinical heart alterations

• Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

  Enrico Agabiti Rosei

• IRCCS Istituto Auxologico Italiano, University of Milano-Bicocca, Milano, Italy

  Giuseppe Mancia

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