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  • © 2008

Electrical Diseases of the Heart

Genetics, Mechanisms, Treatment, Prevention

  • Provides a perspective on primary (heritable) electrical disease of the heart and sudden cardiac death in cardiology, neurology, nephrology, endocrinology by emphasizing the clinical and basic aspects of the physiology and pathophysiology in conjunction with new clinical findings and research discoveries

  • Thought-provoking and enlightening emphases on the latest research and clinical accomplishments

  • Structure of chapters: exposure to the experimental background of each electrical disease, syndrome, and ECG phenomenon stressing the relationship with clinical practice

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Table of contents (69 chapters)

  1. Front Matter

    Pages i-xxvi
  2. Basic Foundations of Normal and Abnormal Cardiac Electrical Activity

    1. Front Matter

      Pages 1-1
    2. Basic Physiology of Ion Channel Function

      • Isabelle Baró, Denis Escande†
      Pages 11-23
    3. Developmental Aspects of the Electrophysiology of the Heart: Function Follows Form

      • Alex V. Postma, Vincent M. Christoffels, Antoon F.M. Moorman
      Pages 24-36
    4. Anatomic and Histopathological Characteristics of the Conductive Tissues of the Heart

      • Cristina Basso, Siew Yen Ho, Gaetano Thiene
      Pages 37-51
    5. Mechanisms of Cardiac Arrhythmia

      • Charles Antzelevitch, Alexander Burashnikov, José M. Di Diego
      Pages 65-132
    6. Mechanisms of Action of Antiarrhythmic Drugs

      • Shingo Murakami, Yoshihisa Kurachi
      Pages 133-144
    7. Sodium Ion Channelopathies

      • Simona Casini, Arthur A. M. Wilde, Hanno L. Tan
      Pages 170-186
    8. L-type Calcium Channel Disease

      • Yanfei Ruan, Raffaella Bloise, Carlo Napolitano, Silvia G. Priori
      Pages 187-193
    9. K+ Channelopathies (I Ks and I Kr)

      • Nicolas Lindegger, Robert S. Kass
      Pages 194-206
    10. Channelopathies of Cardiac Inwardly Rectifying Potassium Channels

      • Andre Terzic, Michel Vivaudou, Christophe Moreau, Timothy M. Olson, Arshad Jahangir, Leonid V. Zingman et al.
      Pages 207-217
    11. Calcium Release Channels (Ryanodine Receptors) and Arrhythmogenesis

      • Subeena Sood, Xander H.T. Wehrens
      Pages 218-231
    12. Caveolae and Arrhythmogenesis

      • Matteo Vatta
      Pages 232-246
    13. Senescence and Arrhythmogenesis

      • Arshad Jahangir, Srinivasan Sattiraju, Win-Kuang Shen
      Pages 247-260
    14. Comparisons of Substrates Responsible for Atrial Versus Ventricular Fibrillation

      • Brett Burstein, Philippe Comtois, Stanley Nattel
      Pages 261-280

About this book

"Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention" provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into 7 major parts. Each part consists of chapters (total of 64) dealing with related topics. Each chapter is outlined with objectives, key points, current perspectives, and recommendations for future investigations and includes established and evidence-based knowledge, the authors' personal opinions, areas of controversy, and future trends.

Reviews

From the reviews:

"This is a thorough reference on the current status of cardiac electrophysiological disease. The book offers a true bridge between the basic and clinical sciences emphasizing common and diverse clinical features. … It is intended for medical residents, cardiology fellows, and cardiologists with an interest in cardiac electrophysiology. The coeditors and numerous contributors are all incredible authorities in the field. … This comprehensive book successfully presents readers with an understanding of the current status of both clinical and experimental cardiac electrophysiology." (Sushant B. Sharma, Doody’s Review Service, April, 2008)

"Ihor Gussak and Charles Antzelevitch, the editors of this book, should be commended for a thoughtful and thorough review of … cardiac electrophysiology. The book contains 63 chapters … . Overall, the chapters are well written, comprehensive, and extensively referenced. The images and figures are clear, well labeled, and relevant. … will serve best when used selectively as a source of information as needed. … a timely and definitive text that will be useful to all who have an interest in cardiac arrhythmia." (N. A. Mark Estes, The New England Journal of Medicine, July, 2008)

Editors and Affiliations

  • Cardiovascular Boehringer Ingelheim Pharmaceuticals Ridgefield, USA

    Ihor Gussak

  • Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Bridgewater, USA

    Ihor Gussak

  • Gordon K. Moe Scholar Masonic Medical Research Laboratory, Utica, USA

    Charles Antzelevitch

  • Upstate Medical University, Syracuse, USA

    Charles Antzelevitch

  • Heart Failure Research Center Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands

    Arthur A. M. Wilde

  • Mayo Clinic College of Medicine, Rochester, USA

    Paul A. Friedman, Michael J. Ackerman

  • Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, USA

    Win-Kuang Shen

Bibliographic Information

  • Book Title: Electrical Diseases of the Heart

  • Book Subtitle: Genetics, Mechanisms, Treatment, Prevention

  • Editors: Ihor Gussak, Charles Antzelevitch, Arthur A. M. Wilde, Paul A. Friedman, Michael J. Ackerman, Win-Kuang Shen

  • DOI: https://doi.org/10.1007/978-1-84628-854-8

  • Publisher: Springer London

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag London 2008

  • eBook ISBN: 978-1-84628-854-8Published: 08 September 2008

  • Edition Number: 1

  • Number of Pages: XX, 600

  • Number of Illustrations: 243 b/w illustrations, 85 illustrations in colour

  • Topics: Cardiology, Epidemiology, Neurology, Internal Medicine

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access