Overview
Provides clear explanations of the complex mechanisms of signal transduction in the human heart
Blends emerging discoveries in basic research with practical clinical applications
Presents a consistent approach to the subject matter
Reflects current post-genomic thinking, introduces new ideas and outlines future directions
Includes supplementary material: sn.pub/extras
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Table of contents (22 chapters)
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Front Matter
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Methodologies
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Front Matter
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Normal Signaling Processes
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Front Matter
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Mitochondria
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Front Matter
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Pediatric Cardiology
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Front Matter
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Aging
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Front Matter
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Signaling in Cardiovascular Disease
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Front Matter
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Signaling in Cardiovascular Disease
Keywords
About this book
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact.
This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Authors and Affiliations
Bibliographic Information
Book Title: Signaling in the Heart
Authors: José Marín-García
DOI: https://doi.org/10.1007/978-1-4419-9461-5
Publisher: Springer New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-4419-9460-8Published: 22 June 2011
Softcover ISBN: 978-1-4899-9576-6Published: 01 October 2014
eBook ISBN: 978-1-4419-9461-5Published: 21 June 2011
Edition Number: 1
Number of Pages: XX, 507
Topics: Cardiology, Medical Biochemistry