Vascular Endothelium

1. Front Matter

   Pages i-x

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2. Free Radicals/Ischemia Reperfusion Injury

   1. Front Matter

      Pages 1-1

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   2. Basal Release of EDRF under Conditions of Oxidant Stress

      • Nandor Marczin, Xilin Chen, John D. Catravas

      Pages 3-16

3. Invasion and Neoplasia

   1. Front Matter

      Pages 17-17

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   2. Interaction of Malaria-Infected Cells with the Vascular Wall

      • Giorgio Senaldi, Fabienne Tacchini-Cottier, Georges E. Grau

      Pages 19-34

   3. Endothelial-Tumor Cell Interactions in Vitro and in Vivo

      • R. Giavazzi, A. Garofalo, I. Martin-Padura, A. J. H. Gearing, E. Dejana

      Pages 35-41

4. Altered Vascular Reactivity

   1. Front Matter

      Pages 43-43

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   2. Altered Vascular Reactivity in Coronary Artery Disease

      • Johannes Zanzinger, Eberhard Bassenge

      Pages 45-54

   3. Coronary Artery and Coronary Artery Bypass Graft Disease: Role of the Endothelium and Vascular Smooth Muscle

      • Thomas F. Lüscher

      Pages 55-71

   4. Isoforms of Nitric Oxide Synthase and the Nitric Oxide-Cyclic Gmp Signal Transduction System

      • Ferid Murad, U. Förstermann, M. Nakane, J. Pollock, H. Schmidt, T. Matsumoto et al.

      Pages 73-80

   5. Regulation of Angiogenesis Via Protein Kinase C

      • Michael E. Maragoudakis, Nikos E. Tsopanoglou, George Haralabopoulos

      Pages 81-85

5. Inflammation/Atherosclerosis

   1. Front Matter

      Pages 87-87

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   2. The Clinical Profile of Atherosclerosis

      • Allan D. Callow

      Pages 89-98

   3. Proinflammatory Role of Leukocyte Adhesion Molecules

      • John M. Harlan, Robert K. Winn, Nicholas B. Vedder

      Pages 99-105

   4. Modulation of Endothelial Cell Function by Cytokines

      • M. Introna, F. Breviario, E. d’Aniello, E. Dejana, Alberto Mantovani

      Pages 107-114

   5. Circulating Endothelial Adhesion Molecules

      • John L. Gordon, R. M. Edwards, S. J. Cashman, A. J. Rees, A. J. H. Gearing

      Pages 115-122

6. Organ Transplantation/Rejection

   1. Front Matter

      Pages 123-123

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   2. Experimental Cell Transplantation and Gene Therapy Techniques in the Treatment of Liver Disease

      • Achilles A. Demetriou, J. Rozga, D. Neuzil, M. Holzman, D. Griffin, Albert D. Moscioni

      Pages 125-133

   3. Modulators of Chronic Rejection

      • Bengt Fellström, Erik Larsson

      Pages 135-143

7. Epilogue

   1. Front Matter

      Pages 145-145

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This book is a compilation of the lectures and oral and poster communications presented at the Advanced Study. Institute on "Vascular Endothelium: Physiological Basis of Clinical Problems II," which took place between June 20 and 30, 1992 in Rhodes, Greece. This third in a series of ASIs on vascular endothelium continued on the theme of the first (1988) ASI on "Receptors and Transduction Mechanisms" and particularly expanded that of the 1990 conference on ''Physiological Basis of Clinical Problems. " We continued the successful practice of bringing together clinicians and scientists: this was reflected equally well in the composition of the organizing committee as in the background of the particiJ?ants. Endothelial cell functions and dysfunctions present as many challenges to the mvestigator as they do to the curious clinical practitioner. As these problems are necessarily different, this unique ten-day co-habitation of these individuals continued to offer fresh outlooks to each, stimulated potential collaborative efforts and, most importantly, advanced --ever so slightly--our knowledge of vascular biology. This year's conference was further enriched by the presence of several of our colleagues from Eastern Europe whom we are delighted to welcome as officially sponsored participants to this and future NATO-supported meetings. It is never superfluous to remind readers and participants that those signing at the bottom of this page, while responsible for many of the ASI's and the book's deficiencies, are but three of the many contributors to the successes.

• atherosclerosis
• biology
• coronary artery disease
• endothelium
• gene therapy
• leukocyte
• transplantation

• Medical College of Georgia, Augusta, USA

  John D. Catravas

• Washington University Medical School, St. Louis, USA

  Allan D. Callow

• T Cell Sciences, Inc., Cambridge, USA

  Una S. Ryan

Policies and ethics