Cardiac Drugs in Pregnancy

1. Front Matter

   Pages i-xii

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2. General Principles and Guidelines

   • John Anthony

   Pages 1-9

3. Management of Hypertension

   • Eckhart J. Buchmann

   Pages 11-34

4. Managing Heart Failure Pre- and Postpartum

   • Karen Sliwa, Kemilembe B. Tibazarwa

   Pages 35-52

5. Management of Coronary Artery Disease and Arrhythmias

   • Annemien E. van den Bosch, Titia P. E. Ruys, Jolien W. Roos-Hesselink

   Pages 53-77

6. Anticoagulation in Pregnancy

   • Vera Regitz-Zagrosek, Christa Gohlke-Baerwolf, Bernard Iung, Petronella G. Pieper

   Pages 79-105

7. Obstetric Drugs in the Management of Cardiovascular Disease

   • Catherine Elliott

   Pages 107-122

8. Back Matter

   Pages 123-131

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​The spectrum of cardiovascular disease affecting women in pregnancy and postpartum is changing and differs between countries. In the western world, the risk of cardiovascular disease in pregnancy has increased due to the increasing age at the first pregnancy and the worldwide obesity epidemic leading also to early diabetes and hypertension. In addition the treatment of congenital heart disease has improved leading to an increased number of women with residual heart disease reaching childbearing age. In the western world maternal heart disease is now the major cause of maternal death during pregnancy. In the developing world rheumatic heart disease and the cardiomyopathies dominate. Those women often need anticoagulation as they might have had a valve replacement or formed a thrombus in the left heart. Drugs during pregnancy and the breastfeeding period is a complex subject and there is a profound shortage of evidence based recommendations. As drug treatment in pregnancy concern the mother and the fetus optimum treatment of both must be targeted. This book aims at discussing the most important indications of drug usage in pregnancy and postpartum with the aim of weighing the potential risk of a drug and the possible benefit against each other.​

• Anticoagulation
• Maternal heart disease
• Postpartum heart disease
• maternal and child health
• pharmacotherapy

“This handy book, written by distinguished authors in the field, consists of six chapters illustrating pharmacological treatment of different heart diseases during pregnancy. … The book is an easy and enjoyable reading. … the content is easily comprehensible and the book has a universal appeal, as it includes treatment in countries with different facilities. In addition, the pocket format is pleasing and practical for the everyday clinician.” (Maria Schaufelberger, European Heart Journal, Vol. 36 (18), 2015)

• Hatter Institute for Cardiovascular Research, Cape Town, South Africa

  Karen Sliwa

• Department of Obstetrics & Gynaecology, Groote Schuur Hospital, Cape Town, South Africa

  John Anthony

Professor Karen Sliwa-Hähnle, MD, PhD, FESC, FACC, DTM&H, is Director of the Hatter Institute for Cardiovascular Research in Africa (HICRA) and Professor at the Department of Medicine and Institute of Infectious Diseases and Molecular Medicine University of Cape Town, South Africa.

Professor John Anthony, MB, ChB, FCOG, MPhil, is Head of the Department of Obstetrics & Gynaecology at Groote Schuur Hospital, Cape Town, South Africa.  

 

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